Relating the chondrocyte gene network to growth plate morphology: from genes to phenotype.
During endochondral ossification, chondrocyte growth and differentiation is controlled by many local signalling pathways. Due to crosstalks and feedback mechanisms, these interwoven pathways display a network like structure. In this study, a large-scale literature based logical model of the growth p...
Main Authors: | Johan Kerkhofs, Scott J Roberts, Frank P Luyten, Hans Van Oosterwyck, Liesbet Geris |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
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Series: | PLoS ONE |
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22558096/?tool=EBI |
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