LC-MS Analysis of Serum for the Metabolomic Investigation of the Effects of Pulchinenoside b4 Administration in Monosodium Urate Crystal-Induced Gouty Arthritis Rat Model

LC-MS Analysis of Serum for the Metabolomic Investigation of the Effects of Pulchinenoside b4 Administration in Monosodium Urate Crystal-Induced Gouty Arthritis Rat Model

Gouty arthritis (GA) is commonly caused by deposition of monosodium urate (MSU) crystals within the joint capsule, bursa, cartilage, bone, or other periarticular tissues after chronic hyperuricemia. Clinically, GA is characterized by acute episodes of joint inflammation, which is most frequently enc...

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Bibliographic Details
Main Authors: Shang Lyu, Ruowen Ding, Peng Liu, Hui OuYang, Yulin Feng, Yi Rao, Shilin Yang
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Molecules
Subjects:
pulchinenoside b4
gouty arthritis
monosodium urate crystal
UPLC-QTOF-MS/MS
metabolomics
pharmacodynamics
pathway
potential biomarkers
multivariate analysis
Online Access:https://www.mdpi.com/1420-3049/24/17/3161

Internet

https://www.mdpi.com/1420-3049/24/17/3161

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