Prophylactic intra-aortic balloon pump in patients with left main disease undergoing off-pump coronary artery bypass grafting
Abstract Background Preventive intra-aortic balloon pump (IABP) for high-risk patients with stable hemodynamics is controversial, and its definition of high-risk is still unclear. This study aimed to investigate the effect of prophylactic IABP on the early outcome of left main disease (LMD) patients...
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doaj-35aa64810cb84fbdb637a624aa7958d52020-11-25T03:54:59ZengBMCBMC Cardiovascular Disorders1471-22612020-06-012011510.1186/s12872-020-01554-6Prophylactic intra-aortic balloon pump in patients with left main disease undergoing off-pump coronary artery bypass graftingJu-Bing Zheng0Kun Hua1Kui Zhang2Shao-You Zhou3Shi-Jun Xu4Juan-Juan Sheng5Ran Dong6Department of Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical UniversityDepartment of Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical UniversityDepartment of Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical UniversityDepartment of Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical UniversityDepartment of Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical UniversityDepartment of Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical UniversityDepartment of Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical UniversityAbstract Background Preventive intra-aortic balloon pump (IABP) for high-risk patients with stable hemodynamics is controversial, and its definition of high-risk is still unclear. This study aimed to investigate the effect of prophylactic IABP on the early outcome of left main disease (LMD) patients receiving off-pump coronary artery bypass grafting (OPCABG) with stable hemodynamics. Methods From January 2013 to April 2020, 257 consecutive patients who underwent OPCABG through sternotomy were enrolled in this study. All LMD patients (greater than 70%) had stable hemodynamics (BP>100 mmHg without vasoconstrictor substance infusion). Early outcomes of 125 patients with prophylactic IABP (IABP group) and 132 patients without IABP (Control group) were compared in this study. Results IABP did not show favorable effect on the conversion to CPB (RR 0.63, 95%CI 0.05–7.89, P = 0.7211), perioperative MI (RR 0.69, 95%CI 0.22–2.12, P = 0.5163), mortality (RR 0.65, 95%CI 0.04–10.25, P = 0.7608) or the composite end of the conversion, MI and mortality (RR 0.63, 95%CI 0.23–1.74, P = 0.3747). There was greater incidence of prolonged ventilation in IABP after adjustment (RR2.16, 95%CI 1.12–4.18, P = 0.0221). There was no IABP-related mortality or limb ischemia. Conclusion No significant difference in early outcomes was observed in hemodynamically stable patients with LMD between prophylactic IABP group and control group. Prophylactic IABP may be unnecessary in patients with LMD undergoing OPCABG.http://link.springer.com/article/10.1186/s12872-020-01554-6Left Main diseaseOff-pump coronary artery bypass graftingIntra-aortic balloon pump |
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DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Ju-Bing Zheng Kun Hua Kui Zhang Shao-You Zhou Shi-Jun Xu Juan-Juan Sheng Ran Dong |
spellingShingle |
Ju-Bing Zheng Kun Hua Kui Zhang Shao-You Zhou Shi-Jun Xu Juan-Juan Sheng Ran Dong Prophylactic intra-aortic balloon pump in patients with left main disease undergoing off-pump coronary artery bypass grafting BMC Cardiovascular Disorders Left Main disease Off-pump coronary artery bypass grafting Intra-aortic balloon pump |
author_facet |
Ju-Bing Zheng Kun Hua Kui Zhang Shao-You Zhou Shi-Jun Xu Juan-Juan Sheng Ran Dong |
author_sort |
Ju-Bing Zheng |
title |
Prophylactic intra-aortic balloon pump in patients with left main disease undergoing off-pump coronary artery bypass grafting |
title_short |
Prophylactic intra-aortic balloon pump in patients with left main disease undergoing off-pump coronary artery bypass grafting |
title_full |
Prophylactic intra-aortic balloon pump in patients with left main disease undergoing off-pump coronary artery bypass grafting |
title_fullStr |
Prophylactic intra-aortic balloon pump in patients with left main disease undergoing off-pump coronary artery bypass grafting |
title_full_unstemmed |
Prophylactic intra-aortic balloon pump in patients with left main disease undergoing off-pump coronary artery bypass grafting |
title_sort |
prophylactic intra-aortic balloon pump in patients with left main disease undergoing off-pump coronary artery bypass grafting |
publisher |
BMC |
series |
BMC Cardiovascular Disorders |
issn |
1471-2261 |
publishDate |
2020-06-01 |
description |
Abstract Background Preventive intra-aortic balloon pump (IABP) for high-risk patients with stable hemodynamics is controversial, and its definition of high-risk is still unclear. This study aimed to investigate the effect of prophylactic IABP on the early outcome of left main disease (LMD) patients receiving off-pump coronary artery bypass grafting (OPCABG) with stable hemodynamics. Methods From January 2013 to April 2020, 257 consecutive patients who underwent OPCABG through sternotomy were enrolled in this study. All LMD patients (greater than 70%) had stable hemodynamics (BP>100 mmHg without vasoconstrictor substance infusion). Early outcomes of 125 patients with prophylactic IABP (IABP group) and 132 patients without IABP (Control group) were compared in this study. Results IABP did not show favorable effect on the conversion to CPB (RR 0.63, 95%CI 0.05–7.89, P = 0.7211), perioperative MI (RR 0.69, 95%CI 0.22–2.12, P = 0.5163), mortality (RR 0.65, 95%CI 0.04–10.25, P = 0.7608) or the composite end of the conversion, MI and mortality (RR 0.63, 95%CI 0.23–1.74, P = 0.3747). There was greater incidence of prolonged ventilation in IABP after adjustment (RR2.16, 95%CI 1.12–4.18, P = 0.0221). There was no IABP-related mortality or limb ischemia. Conclusion No significant difference in early outcomes was observed in hemodynamically stable patients with LMD between prophylactic IABP group and control group. Prophylactic IABP may be unnecessary in patients with LMD undergoing OPCABG. |
topic |
Left Main disease Off-pump coronary artery bypass grafting Intra-aortic balloon pump |
url |
http://link.springer.com/article/10.1186/s12872-020-01554-6 |
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