Chemogenetic ON and OFF switches for RNA virus replication

Therapeutic application of RNA viruses requires tight control over viral activity. Here the authors design a regulatory switch that enables control over activity with clinically approved HIV protease inhibitors.

Bibliographic Details
Main Authors: E. Heilmann, J. Kimpel, B. Hofer, A. Rössler, I. Blaas, L. Egerer, T. Nolden, C. Urbiola, H. G. Kräusslich, G. Wollmann, D. von Laer
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-21630-5

Similar Items