Essential role of the TFIID subunit TAF4 in murine embryogenesis and embryonic stem cell differentiation
The role of TFIID core module TAFs (TATA-binding protein-associated factors) in embryogenesis is unknown. Here, the authors show that Taf4 is essential at mid-gestation and for complete neuronal differentiation of embryonic stem cells, but that Taf4a and Taf4b are redundant at early embryonic stages...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2016-03-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/ncomms11063 |