Creating customized oral stents for head and neck radiotherapy using 3D scanning and printing

• Main Authors: Mohamed Zaid, Nimit Bajaj, Hannah Burrows, Ryan Mathew, Annie Dai, Christopher T. Wilke, Stephen Palasi, Ryan Hergenrother, Caroline Chung, Clifton D. Fuller, Jack Phan, G. Brandon Gunn, William H. Morrison, Adam S. Garden, Steven J. Frank, David I. Rosenthal, Michael Andersen, Adegbenga Otun, Mark S. Chambers, Eugene J. Koay
• Format: Article
• Language: English
• Published: BMC 2019-08-01
• Series: Radiation Oncology
• Subjects: Radiation therapy; 3D printing; 3D scanning; Oral stents; Head and neck cancer
• Online Access: http://link.springer.com/article/10.1186/s13014-019-1357-2

Abstract Background To evaluate and establish a digital workflow for the custom designing and 3D printing of mouth opening tongue-depressing (MOTD) stents for patients receiving radiotherapy for head and neck cancer. Methods We retrospectively identified 3 patients who received radiation therapy (RT) for primary head and neck cancers with MOTD stents. We compared two methods for obtaining the digital impressions of patients’ teeth. The first method involved segmentation from computed tomography (CT) scans, as previously established by our group, and the second method used 3D scanning of the patients’ articulated stone models that were made during the conventional stent fabrication process. Three independent observers repeated the process to obtain digital impressions which provided data to design customized MOTD stents. For each method, we evaluated the time efficiency, dice similarity coefficient (DSC) for reproducibility, and the 3D printed stents’ accuracy. For the 3D scanning method, we evaluated the registration process using manual and automatic approaches. Results For all patients, the 3D scanning method demonstrated a significant advantage over the CT scanning method in terms of time efficiency with over 60% reduction in time consumed (p < 0.0001) and reproducibility with significantly higher DSC (p < 0.001). The printed stents were tested over the articulated dental stone models, and the trueness of fit and accuracy of dental anatomy was found to be significantly better for MOTD stents made using the 3D scanning method. The automated registration showed higher accuracy with errors < 0.001 mm compared to manual registration. Conclusions We developed an efficient workflow for custom designing and 3D-printing MOTD radiation stents. This workflow represents a considerable improvement over the CT-derived segmentation method. The application of this rapid and efficient digital workflow into radiation oncology practices can expand the use of these toxicity sparing devices to practices that do not currently have the support to make them.