Reversal of Cellular Phenotypes in Neural Cells Derived from Huntington’s Disease Monkey-Induced Pluripotent Stem Cells

Reversal of Cellular Phenotypes in Neural Cells Derived from Huntington’s Disease Monkey-Induced Pluripotent Stem Cells

Huntington’s disease (HD) is a dominant neurodegenerative disorder caused by the expansion of glutamine residues in the N-terminal region of the huntingtin (HTT) protein. The disease results in progressive neuronal loss, leading to motor, cognitive, and psychiatric impairment. Here, we report the es...

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Bibliographic Details
Main Authors: Richard L. Carter, Yiju Chen, Tanut Kunkanjanawan, Yan Xu, Sean P. Moran, Kittiphong Putkhao, Jinjing Yang, Anderson H.C. Huang, Rangsun Parnpai, Anthony W.S. Chan
Format: Article
Language:English
Published: Elsevier 2014-10-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671114002410

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