Impact of Type 2 Diabetes Mellitus on Human Bone Marrow Stromal Cell Number and Phenotypic Characteristics

Impact of Type 2 Diabetes Mellitus on Human Bone Marrow Stromal Cell Number and Phenotypic Characteristics

Human bone marrow-derived mesenchymal stromal cells (MSCs) have been investigated in numerous disease settings involving impaired regeneration because of the crucial role they play in tissue maintenance and repair. Considering the number of comorbidities associated with type 2 diabetes mellitus (T2D...

Full description

Bibliographic Details
Main Authors:	Féaron C. Cassidy, Ciara Shortiss, Colin G. Murphy, Stephen R. Kearns, William Curtin, Ciara De Buitléir, Timothy O’Brien, Cynthia M. Coleman
Format:	Article
Language:	English
Published:	MDPI AG 2020-04-01
Series:	International Journal of Molecular Sciences
Subjects:	type 2 diabetes mellitus mesenchymal stem cells mesenchymal stromal cells adult stem cells bone marrow stromal cells
Online Access:	https://www.mdpi.com/1422-0067/21/7/2476

Similar Items

Comparison of endometrial regenerative cells and bone marrow stromal cells
by: Wang Huan, et al.
Published: (2012-10-01)

Multipotent human stromal cells isolated from cord blood, term placenta and adult bone marrow show distinct differences in gene expression pattern
by: Nicholas Matigian, et al.
Published: (2015-03-01)

Editorial: Current Progress in Mesenchymal Stem/Stromal Cell Research
by: Lindolfo da Silva Meirelles, et al.
Published: (2021-02-01)

Low Oxygen Tension Maintains Multipotency, Whereas Normoxia Increases Differentiation of Mouse Bone Marrow Stromal Cells
by: Marco Giorgio, et al.
Published: (2013-01-01)

Mesenchymal Stromal/Stem cells: Historical perspective and ongoing challenges
by: Maria Isabel Doria Rossi, et al.
Published: (2020-06-01)

Characterisation of ovine bone marrow-derived stromal cells (oBMSC) and evaluation of chondrogenically induced micro-pellets for cartilage tissue repair in vivo
by: K. Futrega, et al.
Published: (2021-01-01)

Controlled aggregation enhances immunomodulatory potential of mesenchymal stromal cell aggregates
by: Angela W. Xie, et al.
Published: (2021-08-01)

Effects of acute exposure to low-dose radiation on the characteristics of human bone marrow mesenchymal stromal/stem cells
by: Aya Fujishiro, et al.
Published: (2017-09-01)

Comparison of mesenchymal stem cell surface markers from bone marrow aspirates and adipose stromal vascular fraction sites
by: Meghan eSullivan, et al.
Published: (2016-01-01)

A 3D culture system enhances the ability of human bone marrow stromal cells to support the growth of limbal stem/progenitor cells
by: Sheyla González, et al.
Published: (2016-03-01)

Administration of Human Non-Diabetic Mesenchymal Stromal Cells to a Murine Model of Diabetic Fracture Repair: A Pilot Study
by: Luke Watson, et al.
Published: (2020-06-01)

A magic kick for regeneration: role of mesenchymal stromal cell secretome in spermatogonial stem cell niche recovery
by: Georgy Sagaradze, et al.
Published: (2019-11-01)

Unveiling Mesenchymal Stromal Cells’ Organizing Function in Regeneration
by: Peter P. Nimiritsky, et al.
Published: (2019-02-01)

Adipose-derived stromal cells in regulation of hematopoiesis
by: Jing Zhang, et al.
Published: (2020-03-01)

Bone marrow-derived from the human femoral shaft as a new source of mesenchymal stem/stromal cells: an alternative cell material for banking and clinical transplantation
by: Katarzyna Drela, et al.
Published: (2020-06-01)

Comprehensive Proteomic Analysis and Characterization of Human Bone Marrow Mesenchymal Stem/Stromal Derived Extracellular Vesicles
by: Munshi, Afnan M N Alam
Published: (2019)

Bone marrow mesenchymal stem cells in rheumatoid arthritis, spondyloarthritis, and ankylosing spondylitis: problems rather than solutions?
by: Jean-Marie Berthelot, et al.
Published: (2019-11-01)

Bone Marrow Concentrate Mesenchymal Stromal Cells Do not Correlate With Nucleated Cell Count or Colony Forming Units
by: Marta Cercone, et al.
Published: (2021-09-01)

CLINICAL EFFECTS OF MESENCHYMAL STROMAL CELLS IN LYMPHOMA PATIENTS WITH AUTOLOGOUS HEMATOPOIETIC STEM CELL TRANSPLANTATION
by: E. V. Batorov, et al.
Published: (2012-05-01)

Bone Marrow-Derived HipOP Cell Population Is Markedly Enriched in Osteoprogenitors
by: Jane E. Aubin, et al.
Published: (2012-08-01)

The Metastatic Bone Marrow Niche in Neuroblastoma: Altered Phenotype and Function of Mesenchymal Stromal Cells
by: Caroline Hochheuser, et al.
Published: (2020-11-01)

Comparison of human bone marrow stromal cells cultured in human platelet growth factors and fetal bovine serum
by: Jiaqiang Ren, et al.
Published: (2018-03-01)

Biological characteristics of stem cells derived from burned skin—a comparative study with umbilical cord stem cells
by: Reinhard Dolp, et al.
Published: (2021-02-01)

Intrinsic Angiogenic Potential and Migration Capacity of Human Mesenchymal Stromal Cells Derived from Menstrual Blood and Bone Marrow
by: Rosana de Almeida Santos, et al.
Published: (2020-12-01)

Epigenetic Classification of Human Mesenchymal Stromal Cells
by: Danilo Candido de Almeida, et al.
Published: (2016-02-01)

Percutaneous Autologous Bone Marrow-Derived Mesenchymal Stromal Cell Implantation Is Safe for Reconstruction of Human Lower Limb Long Bone Atrophic Nonunion
by: Mohsen Emadedin, et al.
Published: (2017-01-01)

Angiogenic Effects of Human Dental Pulp and Bone Marrow-Derived Mesenchymal Stromal Cells and their Extracellular Vesicles
by: Greet Merckx, et al.
Published: (2020-01-01)

Role of ex vivo Expanded Mesenchymal Stromal Cells in Determining Hematopoietic Stem Cell Transplantation Outcome
by: Stefania Crippa, et al.
Published: (2021-05-01)

Are MSCs Angiogenic Cells?New Insights on Human Nestin-positive Bone Marrow-derived Multipotent Cells
by: Simone ePacini, et al.
Published: (2014-05-01)

Reciprocal upregulation of Notch signaling molecules in hematopoietic progenitor and mesenchymal stromal cells
by: Kikuchi Y, et al.
Published: (2011-01-01)

Combined therapy with adipose tissue-derived mesenchymal stromal cells and meglumine antimoniate controls lesion development and parasite load in murine cutaneous leishmaniasis caused by Leishmania amazonensis
by: Tadeu Diniz Ramos, et al.
Published: (2020-08-01)

Mesenchymal stem/stromal cells: Developmental origin, tumorigenesis and translational cancer therapeutics
by: Chenghai Li, et al.
Published: (2021-01-01)

Feeder-free generation and transcriptome characterization of functional mesenchymal stromal cells from human pluripotent stem cells
by: Lidan Luo, et al.
Published: (2020-10-01)

Mesenchymal Stromal Cells for Transplant Tolerance
by: Manuel Alfredo Podestà, et al.
Published: (2019-06-01)

A focus on allogeneic mesenchymal stromal cells as a versatile therapeutic tool for treating multiple sclerosis
by: Ameneh Shokati, et al.
Published: (2021-07-01)

Neural differentiation of canine mesenchymal stem cells/multipotent mesenchymal stromal cells
by: Sonja Prpar Mihevc, et al.
Published: (2020-08-01)

Mesenchymal Stromal Cells, a New Player in Reducing Complications From Liver Transplantation?
by: Andrew Owen, et al.
Published: (2020-06-01)

Impact of Three Different Serum Sources on Functional Properties of Equine Mesenchymal Stromal Cells
by: Lynn Pezzanite, et al.
Published: (2021-04-01)

Pharmacological targeting of bone marrow mesenchymal stromal/stem cells for the treatment of hematological disorders
by: Noriko Sugino, et al.
Published: (2017-04-01)

Adipose tissue-derived mesenchymal stromal cells for treating chronic kidney disease: A pilot study assessing safety and clinical feasibility
by: Sandra Villanueva, et al.
Published: (2019-06-01)