Transcriptome analysis of the zebrafish atoh7−/− Mutant, lakritz, highlights Atoh7‐dependent genetic networks with potential implications for human eye diseases

Transcriptome analysis of the zebrafish atoh7−/− Mutant, lakritz, highlights Atoh7‐dependent genetic networks with potential implications for human eye diseases

Abstract Expression of the bHLH transcription protein Atoh7 is a crucial factor conferring competence to retinal progenitor cells for the development of retinal ganglion cells. Several studies have emerged establishing ATOH7 as a retinal disease gene. Remarkably, such studies uncovered ATOH7 variant...

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Bibliographic Details
Main Authors: Giuseppina Covello, Fernando J. Rossello, Michele Filosi, Felipe Gajardo, Anne‐Laure Duchemin, Beatrice F. Tremonti, Michael Eichenlaub, Jose M. Polo, David Powell, John Ngai, Miguel L. Allende, Enrico Domenici, Mirana Ramialison, Lucia Poggi
Format: Article
Language:English
Published: Wiley 2020-07-01
Series:FASEB BioAdvances
Subjects:
Ath5
human retina
inherited eye diseases
retinal ganglion cells
transcriptome analysis
Online Access:https://doi.org/10.1096/fba.2020-00030

Internet

https://doi.org/10.1096/fba.2020-00030

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