CUX1 Enhances Pancreatic Cancer Formation by Synergizing with KRAS and Inducing MEK/ERK-Dependent Proliferation
The transcription factor CUX1 has been implicated in either tumor suppression or progression, depending on the cancer entity and the prevalent CUX1 isoform. Previously, we could show that CUX1 acts as an important mediator of tumor cell proliferation and resistance to apoptosis in pancreatic cancer...
Main Authors: | Heidi Griesmann, Sebastian Mühl, Jan Riedel, Katharina Theuerkorn, Bence Sipos, Irene Esposito, Gregory B. Vanden Heuvel, Patrick Michl |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-05-01
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Series: | Cancers |
Subjects: | |
Online Access: | https://www.mdpi.com/2072-6694/13/10/2462 |
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