mRNA-programmed translation pauses in the targeting of E. coli membrane proteins

In all living organisms, ribosomes translating membrane proteins are targeted to membrane translocons early in translation, by the ubiquitous signal recognition particle (SRP) system. In eukaryotes, the SRP Alu domain arrests translation elongation of membrane proteins until targeting is complete. C...

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Bibliographic Details
Main Authors: Nir Fluman, Sivan Navon, Eitan Bibi, Yitzhak Pilpel
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2014-08-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/03440