Drug holiday in patients with polycystic liver disease treated with somatostatin analogues

Drug holiday in patients with polycystic liver disease treated with somatostatin analogues

Background: Somatostatin analogues (SAs) reduce liver volume and relief symptoms in polycystic liver disease (PLD). Its effect wears off after continuing therapy suggesting development of SA tolerance in patients on chronic therapy. We postulate that a drug holiday resensitizes the liver to its acut...

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Bibliographic Details
Main Authors: René M. M. van Aerts, Marieke Kolkman, Wietske Kievit, Tom J. G. Gevers, Frederik Nevens, Joost P. H. Drenth
Format: Article
Language:English
Published: SAGE Publishing 2018-10-01
Series:Therapeutic Advances in Gastroenterology
Online Access:https://doi.org/10.1177/1756284818804784

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