Trans-Binding Mechanism of Ubiquitin-like Protein Activation Revealed by a UBA5-UFM1 Complex

Modification of proteins by ubiquitin or ubiquitin-like proteins (UBLs) is a critical cellular process implicated in a variety of cellular states and outcomes. A prerequisite for target protein modification by a UBL is the activation of the latter by activating enzymes (E1s). Here, we present the cr...

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Bibliographic Details
Main Authors: Walaa Oweis, Prasanth Padala, Fouad Hassouna, Einav Cohen-Kfir, Dalton R. Gibbs, Emily A. Todd, Christopher E. Berndsen, Reuven Wiener
Format: Article
Language:English
Published: Elsevier 2016-09-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124716311482