Increased vimentin mRNA expression in MCF-7 breast cancer cell line after repeated endoxifen-treatment

Increased vimentin mRNA expression in MCF-7 breast cancer cell line after repeated endoxifen-treatment

Background: Epithelial mesenchymal transition (EMT) plays a significant role in the development of cancer cell resistance to drugs. Vimentin, a type III intermediate filament protein, is a marker of EMT. Vimentin's over-expression in cancer correlates well with increased tumor growth, change i...

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Bibliographic Details
Main Authors: Paramita Paramita, Melva Louisa, Nafrialdi Nafrialdi
Format: Article
Language:English
Published: Faculty of Medicine Universitas Indonesia 2017-01-01
Series:Medical Journal of Indonesia
Subjects:
endoxifen
EMT
vimentin
Online Access:http://mji.ui.ac.id/journal/index.php/mji/article/view/1397

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