Neonatal thrush of newborns: Oral candidiasis?
Abstract Objectives Neonatal thrush, also called oral candidiasis, is commonly a clinical diagnosis based on white patches on oral mucosal surfaces. Candida albicans is often associated with it. This clinical study aimed to investigate the presence of C. albicans among newborns with or without clini...
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doaj-36860dccd3294af1ae7219136598e7482020-11-24T21:54:49ZengWileyClinical and Experimental Dental Research2057-43472019-10-015558058210.1002/cre2.213Neonatal thrush of newborns: Oral candidiasis?Anne Vainionpää0Jenni Tuomi1Saara Kantola2Vuokko Anttonen3Research Unit of Oral Health Sciences University of Oulu Oulu FinlandResearch Unit of Oral Health Sciences University of Oulu Oulu FinlandDepartment of Oral and Maxillofacial Diseases Oulu University Hospital Oulu FinlandResearch Unit of Oral Health Sciences University of Oulu Oulu FinlandAbstract Objectives Neonatal thrush, also called oral candidiasis, is commonly a clinical diagnosis based on white patches on oral mucosal surfaces. Candida albicans is often associated with it. This clinical study aimed to investigate the presence of C. albicans among newborns with or without clinical findings of candidiasis on oral mucosa. Another aim was to investigate how thrush responded to current therapy by acidic liquids such as lingonberry or lemon juice. Material and methods Swipe samples were collected from 32 healthy, full‐term infants younger than 12 months with or without white patches on oral mucosa. Clinical diagnosis of thrush was made by a community nurse based on thick and yellowish white patches. The routine therapy was oral lingonberry or lemon juice or soda water. Disappearing of patches was controlled by a phone call about 2 weeks after the baseline. Both parents and nurses gave background factors by filling a questionnaire. Results One (3%) infant without clinical signs was diagnosed with Candida parapsilosis, none with C. albicans. Thrush resembling candidiasis was diagnosed clinically in four (12.5%) children. Three out of four parents reported persisting findings after 2 weeks. Only the maternal mastitis and use of antibiotics were significantly associated with thrush (p = .001). C. albicans was not discovered from babies with clinical thrush. Conclusions Aetiology of the white patches remained unclear. The current way of treating them with acidic liquids is not efficient. Additional studies are needed.https://doi.org/10.1002/cre2.213Candida albicansinfantnewbornoral candidiasisthrush |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Anne Vainionpää Jenni Tuomi Saara Kantola Vuokko Anttonen |
spellingShingle |
Anne Vainionpää Jenni Tuomi Saara Kantola Vuokko Anttonen Neonatal thrush of newborns: Oral candidiasis? Clinical and Experimental Dental Research Candida albicans infant newborn oral candidiasis thrush |
author_facet |
Anne Vainionpää Jenni Tuomi Saara Kantola Vuokko Anttonen |
author_sort |
Anne Vainionpää |
title |
Neonatal thrush of newborns: Oral candidiasis? |
title_short |
Neonatal thrush of newborns: Oral candidiasis? |
title_full |
Neonatal thrush of newborns: Oral candidiasis? |
title_fullStr |
Neonatal thrush of newborns: Oral candidiasis? |
title_full_unstemmed |
Neonatal thrush of newborns: Oral candidiasis? |
title_sort |
neonatal thrush of newborns: oral candidiasis? |
publisher |
Wiley |
series |
Clinical and Experimental Dental Research |
issn |
2057-4347 |
publishDate |
2019-10-01 |
description |
Abstract Objectives Neonatal thrush, also called oral candidiasis, is commonly a clinical diagnosis based on white patches on oral mucosal surfaces. Candida albicans is often associated with it. This clinical study aimed to investigate the presence of C. albicans among newborns with or without clinical findings of candidiasis on oral mucosa. Another aim was to investigate how thrush responded to current therapy by acidic liquids such as lingonberry or lemon juice. Material and methods Swipe samples were collected from 32 healthy, full‐term infants younger than 12 months with or without white patches on oral mucosa. Clinical diagnosis of thrush was made by a community nurse based on thick and yellowish white patches. The routine therapy was oral lingonberry or lemon juice or soda water. Disappearing of patches was controlled by a phone call about 2 weeks after the baseline. Both parents and nurses gave background factors by filling a questionnaire. Results One (3%) infant without clinical signs was diagnosed with Candida parapsilosis, none with C. albicans. Thrush resembling candidiasis was diagnosed clinically in four (12.5%) children. Three out of four parents reported persisting findings after 2 weeks. Only the maternal mastitis and use of antibiotics were significantly associated with thrush (p = .001). C. albicans was not discovered from babies with clinical thrush. Conclusions Aetiology of the white patches remained unclear. The current way of treating them with acidic liquids is not efficient. Additional studies are needed. |
topic |
Candida albicans infant newborn oral candidiasis thrush |
url |
https://doi.org/10.1002/cre2.213 |
work_keys_str_mv |
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