Association between dynamic changes in HBsAg and progression of chronic hepatitis B

With the application of HBsAg quantification in clinical practice, recent studies have found that HBsAg level can not only reflect the transcriptional activity of double-stranded covalently closed circular DNA, but also predict the risk of disease progression and response to antiviral therapy in pat...

Full description

Bibliographic Details
Main Authors: WANG Wei, RONG Jun, LI Lihua
Format: Article
Language:zho
Published: Editorial Department of Journal of Clinical Hepatology 2016-05-01
Series:Linchuang Gandanbing Zazhi
Online Access:http://www.lcgdbzz.org/qk_content.asp?id=7476
Description
Summary:With the application of HBsAg quantification in clinical practice, recent studies have found that HBsAg level can not only reflect the transcriptional activity of double-stranded covalently closed circular DNA, but also predict the risk of disease progression and response to antiviral therapy in patients with chronic HBV infection. This article reviews the changes in HBsAg level in the natural course of HBV infection and points out the changes in HBsAg level can provide new ideas to the treatment of chronic hepatitis B.
ISSN:1001-5256
1001-5256