Seroprevalence of anti-hepatitis E virus antibodies in domestic pigs in Mexico
Abstract Background Hepatitis E virus (HEV) infection is one of the most common causes of acute liver diseases in humans worldwide. In developing countries, HEV is commonly associated with waterborne outbreaks. Conversely, in industrialized countries, HEV infection is often associated with travel to...
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doaj-3697025176474fdbb62b69a25576a9682020-11-24T21:02:16ZengBMCBMC Veterinary Research1746-61482017-09-011311510.1186/s12917-017-1208-zSeroprevalence of anti-hepatitis E virus antibodies in domestic pigs in MexicoMontserrat Elemi García-Hernández0Mayra Cruz-Rivera1José Iván Sánchez-Betancourt2Oscar Rico-Chávez3Arely Vergara-Castañeda4María E. Trujillo5Rosa Elena Sarmiento-Silva6Facultad de Medicina Veterinaria y Zootecnia, Universidad Nacional Autónoma de MéxicoFacultad de Medicina, Universidad Nacional Autónoma de MéxicoFacultad de Medicina Veterinaria y Zootecnia, Universidad Nacional Autónoma de MéxicoFacultad de Medicina Veterinaria y Zootecnia, Universidad Nacional Autónoma de MéxicoFacultad de Ciencias Químicas, Universidad La SalleFacultad de Medicina Veterinaria y Zootecnia, Universidad Nacional Autónoma de MéxicoFacultad de Medicina Veterinaria y Zootecnia, Universidad Nacional Autónoma de MéxicoAbstract Background Hepatitis E virus (HEV) infection is one of the most common causes of acute liver diseases in humans worldwide. In developing countries, HEV is commonly associated with waterborne outbreaks. Conversely, in industrialized countries, HEV infection is often associated with travel to endemic regions or ingestion of contaminated animal products. Limited information on both, human and animal HEV infection in Mexico is available. As a consequence, the distribution of the virus in the country is largely unknown. Here, we assessed the seroprevalence of HEV among swine in different geographical regions in Mexico. Methods Seroprevalence of anti-HEV antibodies in swine herds in Mexico was evaluated in a representative sample including 945 pig serum specimens from different regions of the country using a commercial enzyme-linked immunosorbent assay (ELISA). Results The overall prevalence of anti-HEV antibodies in swine was 59.4%. The northern region of Mexico exhibited the highest seroprevalence in the country (86.6%), while the central and southern regions in Mexico showed lower seroprevalence, 42.7% and 51.5%, respectively. Conclusions In Mexico, HEV seroprevalence in swine is high. Importantly, northern Mexico showed the highest seroprevalence in the country. Thus, further studies are required to identify the risk factors contributing to HEV transmission among pigs in the country. Assessment of HEV human infection in the context of viral transmission in swine is required to better understand the epidemiology of hepatitis E in Mexico.http://link.springer.com/article/10.1186/s12917-017-1208-zHEVMexicoPigsSeroprevalence |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Montserrat Elemi García-Hernández Mayra Cruz-Rivera José Iván Sánchez-Betancourt Oscar Rico-Chávez Arely Vergara-Castañeda María E. Trujillo Rosa Elena Sarmiento-Silva |
spellingShingle |
Montserrat Elemi García-Hernández Mayra Cruz-Rivera José Iván Sánchez-Betancourt Oscar Rico-Chávez Arely Vergara-Castañeda María E. Trujillo Rosa Elena Sarmiento-Silva Seroprevalence of anti-hepatitis E virus antibodies in domestic pigs in Mexico BMC Veterinary Research HEV Mexico Pigs Seroprevalence |
author_facet |
Montserrat Elemi García-Hernández Mayra Cruz-Rivera José Iván Sánchez-Betancourt Oscar Rico-Chávez Arely Vergara-Castañeda María E. Trujillo Rosa Elena Sarmiento-Silva |
author_sort |
Montserrat Elemi García-Hernández |
title |
Seroprevalence of anti-hepatitis E virus antibodies in domestic pigs in Mexico |
title_short |
Seroprevalence of anti-hepatitis E virus antibodies in domestic pigs in Mexico |
title_full |
Seroprevalence of anti-hepatitis E virus antibodies in domestic pigs in Mexico |
title_fullStr |
Seroprevalence of anti-hepatitis E virus antibodies in domestic pigs in Mexico |
title_full_unstemmed |
Seroprevalence of anti-hepatitis E virus antibodies in domestic pigs in Mexico |
title_sort |
seroprevalence of anti-hepatitis e virus antibodies in domestic pigs in mexico |
publisher |
BMC |
series |
BMC Veterinary Research |
issn |
1746-6148 |
publishDate |
2017-09-01 |
description |
Abstract Background Hepatitis E virus (HEV) infection is one of the most common causes of acute liver diseases in humans worldwide. In developing countries, HEV is commonly associated with waterborne outbreaks. Conversely, in industrialized countries, HEV infection is often associated with travel to endemic regions or ingestion of contaminated animal products. Limited information on both, human and animal HEV infection in Mexico is available. As a consequence, the distribution of the virus in the country is largely unknown. Here, we assessed the seroprevalence of HEV among swine in different geographical regions in Mexico. Methods Seroprevalence of anti-HEV antibodies in swine herds in Mexico was evaluated in a representative sample including 945 pig serum specimens from different regions of the country using a commercial enzyme-linked immunosorbent assay (ELISA). Results The overall prevalence of anti-HEV antibodies in swine was 59.4%. The northern region of Mexico exhibited the highest seroprevalence in the country (86.6%), while the central and southern regions in Mexico showed lower seroprevalence, 42.7% and 51.5%, respectively. Conclusions In Mexico, HEV seroprevalence in swine is high. Importantly, northern Mexico showed the highest seroprevalence in the country. Thus, further studies are required to identify the risk factors contributing to HEV transmission among pigs in the country. Assessment of HEV human infection in the context of viral transmission in swine is required to better understand the epidemiology of hepatitis E in Mexico. |
topic |
HEV Mexico Pigs Seroprevalence |
url |
http://link.springer.com/article/10.1186/s12917-017-1208-z |
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