Zika viruses of African and Asian lineages cause fetal harm in a mouse model of vertical transmission.

Zika viruses of African and Asian lineages cause fetal harm in a mouse model of vertical transmission.

Congenital Zika virus (ZIKV) infection was first linked to birth defects during the American outbreak in 2015/2016. It has been proposed that mutations unique to the Asian/American-genotype explain, at least in part, the ability of Asian/American ZIKV to cause congenital Zika syndrome (CZS). Recent...

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Bibliographic Details
Main Authors: Anna S Jaeger, Reyes A Murrieta, Lea R Goren, Chelsea M Crooks, Ryan V Moriarty, Andrea M Weiler, Sierra Rybarczyk, Matthew R Semler, Christopher Huffman, Andres Mejia, Heather A Simmons, Michael Fritsch, Jorge E Osorio, Jens C Eickhoff, Shelby L O'Connor, Gregory D Ebel, Thomas C Friedrich, Matthew T Aliota
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-04-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0007343

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