Admixture mapping and subsequent fine-mapping suggests a biologically relevant and novel association on chromosome 11 for type 2 diabetes in African Americans.

Admixture mapping and subsequent fine-mapping suggests a biologically relevant and novel association on chromosome 11 for type 2 diabetes in African Americans.

Type 2 diabetes (T2D) is a complex metabolic disease that disproportionately affects African Americans. Genome-wide association studies (GWAS) have identified several loci that contribute to T2D in European Americans, but few studies have been performed in admixed populations. We first performed a G...

Full description

Bibliographic Details
Main Authors: Janina M Jeff, Loren L Armstrong, Marylyn D Ritchie, Joshua C Denny, Abel N Kho, Melissa A Basford, Wendy A Wolf, Jennifer A Pacheco, Rongling Li, Rex L Chisholm, Dan M Roden, M Geoffrey Hayes, Dana C Crawford
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3940426?pdf=render

Internet

http://europepmc.org/articles/PMC3940426?pdf=render

Similar Items