The RNA-Binding Protein RBM3 Promotes Neural Stem Cell (NSC) Proliferation Under Hypoxia

The RNA-Binding Protein RBM3 Promotes Neural Stem Cell (NSC) Proliferation Under Hypoxia

Neural stem cells (NSCs) reside physiologically in a hypoxic niche to maintain self-renewal and multipotency. Whereas mild hypoxia is known to promote NSC proliferation, severe hypoxia in pathological conditions exerts the reverse effect. The multi-functional RNA-binding protein RBM3 is abundant in...

Full description

Bibliographic Details
Main Authors: Jingyi Yan, Tessa Goerne, Andrea Zelmer, Raphael Guzman, Josef P. Kapfhammer, Sven Wellmann, Xinzhou Zhu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
RBM3
CIRP
oxygen
neural stem cell
cell cycle
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2019.00288/full

Similar Items

Similar Items