Evaluation of mouse embryos produced in vitro after electromagnetic waves exposure; Morphometric study
Introduction: Today, the use of electromagnetic waves in medical diagnostic devices, such as magnetic resonance imaging (MRI), has increased, and many of its biological effects have been reported. The aim of the present study was to assess the biological effects of 1.5 Tesla (T) magnetic resonance...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Electronic Physician
2016-01-01
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Series: | Electronic Physician |
Subjects: | |
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768917/ |
Summary: | Introduction: Today, the use of electromagnetic waves in medical diagnostic devices, such as magnetic
resonance imaging (MRI), has increased, and many of its biological effects have been reported. The aim of the
present study was to assess the biological effects of 1.5 Tesla (T) magnetic resonance imaging (MRI) on fertility
and reproductive parameters.
Methods: Eighty adult male and female NMRI mice (NMRI: Naval Medical Research Institute) of age 6-8 weeks
were studied and randomly divided into two study and control groups. After confirmation of pregnancy, the mice
in the study group were exposed to the MRI (1.5 T) machine’s waves over the next three weeks, once a week for
36 minutes. One day and thirty-five days after the last radiation, the mice were killed in order to do the in vitro
fertilization (IVF) by neck beads’ displacement and the impact on the evolution of embryos, and its quality was
studied. Data were analyzed using SPSS version 20 and the significance level of less than 0.05 was considered.
Results: Embryo morphometry showed that the total diameter and the cytoplasm diameter of the study group
embryos suffered significant reduction compared to the control group, 1 day after the last irradiation (p < 0.05),
but the diameter of the perivitelline space of this group’s embryos had a significant increase (p < 0.05). The
qualitative results during 35 days after irradiation showed that morphologically parameters of the embryos in the
study group had no significant differences from the control group.
Conclusion: Exposure to MRI irradiation can transiently disturb the development of mouse embryos and fertility,
but these effects are reversible 35 days after the last irradiation. |
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ISSN: | 2008-5842 2008-5842 |