Hippocampal granule cell loss in human chronic alcohol abusers

Hippocampal granule cell loss in human chronic alcohol abusers

Chronic alcohol abuse causes cognitive impairments associated with neurodegeneration and volume loss in the human hippocampus. Here, we hypothesize that alcohol reduces the number of granule cells in the human dentate gyrus and consequently contribute to the observed volume loss. Hippocampal samples...

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Bibliographic Details
Main Authors: Gopalakrishnan Dhanabalan, Tara Wardi Le Maître, Nenad Bogdanovic, Kanar Alkass, Henrik Druid
Format: Article
Language:English
Published: Elsevier 2018-12-01
Series:Neurobiology of Disease
Subjects:
Addiction
Alcohol abuse
Dentate gyrus
Neurons
Granule cells
Hippocampus
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996118304820

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