Carbapenem Resistance Profile of Acinetobacter baumannii Complex Strains in the Intensive Care Unit of a University Hospital in Northern Cyprus: 3-Year Follow-up
Objective:This study aimed to investigate the distribution of three-year carbapenem resistance of Acinetobacter baumannii complex (ABC) in hospital infections isolated from the intensive care unit in the last three years.Materials and Methods:The patients who had ABC infection in the Intensive Care...
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Galenos Yayinevi
2021-09-01
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doaj-370cc69d21de4e28967a39bdbbc732cd2021-09-01T06:34:19ZengGalenos YayineviTürk Yoğun Bakim Derneği Dergisi2146-64162147-267X2021-09-0119311812210.4274/tybd.galenos.2019.7232413049054Carbapenem Resistance Profile of Acinetobacter baumannii Complex Strains in the Intensive Care Unit of a University Hospital in Northern Cyprus: 3-Year Follow-upMeryem Güvenir0Emrah Güler1Kaya Süer2 Yakın Doğu Üniversitesi, Sağlık Hizmetleri Meslek Yüksekokulu, Mikrobiyoloji Bölümü, Lefkoşa, KKTC Yakın Doğu Üniversitesi Tıp Fakültesi, Tıbbi ve Klinik Mikrobiyoloji Anabilim Dalı, Lefkoşa, KKTC Yakın Doğu Üniversitesi Tıp Fakültesi, Enfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Anabilim Dalı, Lefkoşa, KKTC Objective:This study aimed to investigate the distribution of three-year carbapenem resistance of Acinetobacter baumannii complex (ABC) in hospital infections isolated from the intensive care unit in the last three years.Materials and Methods:The patients who had ABC infection in the Intensive Care Unit of Near East University Hospital between 2016-2018 were included in this study. The data of the patients were investigated retrospectively from the digital records and the Infection Control Committee data. The initial infection report of the patients who had multiple ABC infections was included in the study. SPSS Statistics 23.0 program was used for statistical analysis.Results:A total of 92 patients were diagnosed with ABC infection during the study period, including 22 (23.9%) in 2016, 31 (33.7%) in 2017 and 39 (42.4%) in 2018. Fifty-six patients (60.9%) were male and 36 (39.1%) were female. The mean age of the patients was 61.61±17.43 years (range, 22-89 years). The most common isolates were from tracheal aspirate (28.3%, 26 patients), sputum 27.2%, 25 patients) and urine samples (23.9%, 22 patients). Carbapenem-resistant ABC infection was detected in 65 patients (70.7%) and carbapenemsensitive ABC infection was found in 27 patients (29.3%). There was a statistically significant increase in carbapenem-resistant ABC strains over the years (p<0.05, p=0.012). Thirty-one of the 38 carbapenem-resistant patients were dead.Conclusion:ABC strains that cause high mortality infections can develop resistance to many antibiotic groups very quickly. Therefore, fatality due to multiple antibiotic-resistant ABC strains is increasing all over the world. It was seen that ABC infections had increased in our hospital over years. In parallel, there was a statistically significant increase in carbapenem-resistant ABC strains. Nowadays, it is essential to ensure proper application of isolation rules, to provide relevant personnel training and to prevent ABC infections with rational antibiotic use. http://www.turkishjic.org/archives/archive-detail/article-preview/carbapenem-resistance-profile-of-iacinetobacter-ba/30796 acinetobacter baumanii complexantimicrobial resistanceintensive care unit |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Meryem Güvenir Emrah Güler Kaya Süer |
spellingShingle |
Meryem Güvenir Emrah Güler Kaya Süer Carbapenem Resistance Profile of Acinetobacter baumannii Complex Strains in the Intensive Care Unit of a University Hospital in Northern Cyprus: 3-Year Follow-up Türk Yoğun Bakim Derneği Dergisi acinetobacter baumanii complex antimicrobial resistance intensive care unit |
author_facet |
Meryem Güvenir Emrah Güler Kaya Süer |
author_sort |
Meryem Güvenir |
title |
Carbapenem Resistance Profile of Acinetobacter baumannii Complex Strains in the Intensive Care Unit of a University Hospital in Northern Cyprus: 3-Year Follow-up |
title_short |
Carbapenem Resistance Profile of Acinetobacter baumannii Complex Strains in the Intensive Care Unit of a University Hospital in Northern Cyprus: 3-Year Follow-up |
title_full |
Carbapenem Resistance Profile of Acinetobacter baumannii Complex Strains in the Intensive Care Unit of a University Hospital in Northern Cyprus: 3-Year Follow-up |
title_fullStr |
Carbapenem Resistance Profile of Acinetobacter baumannii Complex Strains in the Intensive Care Unit of a University Hospital in Northern Cyprus: 3-Year Follow-up |
title_full_unstemmed |
Carbapenem Resistance Profile of Acinetobacter baumannii Complex Strains in the Intensive Care Unit of a University Hospital in Northern Cyprus: 3-Year Follow-up |
title_sort |
carbapenem resistance profile of acinetobacter baumannii complex strains in the intensive care unit of a university hospital in northern cyprus: 3-year follow-up |
publisher |
Galenos Yayinevi |
series |
Türk Yoğun Bakim Derneği Dergisi |
issn |
2146-6416 2147-267X |
publishDate |
2021-09-01 |
description |
Objective:This study aimed to investigate the distribution of three-year carbapenem resistance of Acinetobacter baumannii complex (ABC) in hospital infections isolated from the intensive care unit in the last three years.Materials and Methods:The patients who had ABC infection in the Intensive Care Unit of Near East University Hospital between 2016-2018 were included in this study. The data of the patients were investigated retrospectively from the digital records and the Infection Control Committee data. The initial infection report of the patients who had multiple ABC infections was included in the study. SPSS Statistics 23.0 program was used for statistical analysis.Results:A total of 92 patients were diagnosed with ABC infection during the study period, including 22 (23.9%) in 2016, 31 (33.7%) in 2017 and 39 (42.4%) in 2018. Fifty-six patients (60.9%) were male and 36 (39.1%) were female. The mean age of the patients was 61.61±17.43 years (range, 22-89 years). The most common isolates were from tracheal aspirate (28.3%, 26 patients), sputum 27.2%, 25 patients) and urine samples (23.9%, 22 patients). Carbapenem-resistant ABC infection was detected in 65 patients (70.7%) and carbapenemsensitive ABC infection was found in 27 patients (29.3%). There was a statistically significant increase in carbapenem-resistant ABC strains over the years (p<0.05, p=0.012). Thirty-one of the 38 carbapenem-resistant patients were dead.Conclusion:ABC strains that cause high mortality infections can develop resistance to many antibiotic groups very quickly. Therefore, fatality due to multiple antibiotic-resistant ABC strains is increasing all over the world. It was seen that ABC infections had increased in our hospital over years. In parallel, there was a statistically significant increase in carbapenem-resistant ABC strains. Nowadays, it is essential to ensure proper application of isolation rules, to provide relevant personnel training and to prevent ABC infections with rational antibiotic use. |
topic |
acinetobacter baumanii complex antimicrobial resistance intensive care unit |
url |
http://www.turkishjic.org/archives/archive-detail/article-preview/carbapenem-resistance-profile-of-iacinetobacter-ba/30796
|
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