Chemotherapeutic and targeted agents can modulate the tumor microenvironment and increase the efficacy of immune checkpoint blockades

Abstract The development of immune checkpoint blockade (ICB)-based immunotherapy has dramatically changed methods of cancer treatment. This approach triggers a durable treatment response and prolongs patients' survival; however, not all patients can benefit. Accumulating evidence demonstrated t...

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Bibliographic Details
Main Authors: Jun-Yan Li, Yu-Pei Chen, Ying-Qin Li, Na Liu, Jun Ma
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Molecular Cancer
Subjects:
Online Access:https://doi.org/10.1186/s12943-021-01317-7