Analysis of Pharmaceutical Excipient MCC Avicel PH102 Using Compaction Equations

Analysis of Pharmaceutical Excipient MCC Avicel PH102 Using Compaction Equations

This paper focuses on the characterization of the tabletting process and analysis one of the most common pharmaceutical excipients MCC Avicel PH102 by Heckel, Kawakita, Cooper-Eaton and Adams compaction equations. Experimental material was determined by measuring its parameters as particle size dist...

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Bibliographic Details
Main Authors: Peciar Peter, Eckert Maroš, Fekete Roman, Hrnčiar Viliam
Format: Article
Language:English
Published: Sciendo 2016-07-01
Series:Journal of Mechanical Engineering
Subjects:
compaction equation
tabletting
angle of internal friction
angle of wall friction
Online Access:https://doi.org/10.1515/scjme-2016-0012
Description
Summary:This paper focuses on the characterization of the tabletting process and analysis one of the most common pharmaceutical excipients MCC Avicel PH102 by Heckel, Kawakita, Cooper-Eaton and Adams compaction equations. Experimental material was determined by measuring its parameters as particle size distribution, angle of wall friction and flow properties and for more detailed characteristics of the material particles, microscopy images of the powder before and after compressing were created.
ISSN:2450-5471

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