HOXA5 Participates in Brown Adipose Tissue and Epaxial Skeletal Muscle Patterning and in Brown Adipocyte Differentiation

HOXA5 Participates in Brown Adipose Tissue and Epaxial Skeletal Muscle Patterning and in Brown Adipocyte Differentiation

Brown adipose tissue (BAT) plays critical thermogenic, metabolic and endocrine roles in mammals, and aberrant BAT function is associated with metabolic disorders including obesity and diabetes. The major BAT depots are clustered at the neck and forelimb levels, and arise largely within the dermomyot...

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Bibliographic Details
Main Authors: Miriam A. Holzman, Abigail Ryckman, Tova M. Finkelstein, Kim Landry-Truchon, Kyra A. Schindler, Jenna M. Bergmann, Lucie Jeannotte, Jennifer H. Mansfield
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Hoxa5
brown adipose tissue
adipose development
skeletal muscle development
differentiation
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.632303/full

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