Maturation of Mitochondrially Targeted Prx V Involves a Second Cleavage by Mitochondrial Intermediate Peptidase That Is Sensitive to Inhibition by H<sub>2</sub>O<sub>2</sub>
Prx V mRNA contains two in-frame AUG codons, producing a long (L-Prx V) and short form of Prx V (S-Prx V), and mouse L-Prx V is expressed as a precursor protein containing a 49-amino acid N-terminal mitochondria targeting sequence. Here, we show that the N-terminal 41-residue sequence of L-Prx V is...
Main Authors: | Juhyun Sim, Jiyoung Park, Hyun Ae Woo, Sue Goo Rhee |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-02-01
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Series: | Antioxidants |
Subjects: | |
Online Access: | https://www.mdpi.com/2076-3921/10/3/346 |
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