Cross-sectional study about perioperative management of Blood Pressure and effects of anaesthesia in hypertensive patients undergoing general & orthopaedic surgery

Introduction: Hypertension is regarded as an additional risk factor during anaesthesia. There is not enough Indian evidence in literature regarding antihypertensive usage and its implications during perioperative period in patients undergoing general & orthopedic surgery. This drove us to conduc...

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Main Authors: Paresh Girdharlal Koli, Yashashri Shetty, Sweta Salgaonkar, Minakshi Dongre, Sankalp Arora
Format: Article
Language:English
Published: Taylor & Francis Group 2018-07-01
Series:Egyptian Journal of Anaesthesia
Online Access:http://www.sciencedirect.com/science/article/pii/S1110184917303318
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spelling doaj-375e5290727e4cc9b97254b804b551562020-11-24T21:22:37ZengTaylor & Francis GroupEgyptian Journal of Anaesthesia1110-18492018-07-013438993Cross-sectional study about perioperative management of Blood Pressure and effects of anaesthesia in hypertensive patients undergoing general & orthopaedic surgeryParesh Girdharlal Koli0Yashashri Shetty1Sweta Salgaonkar2Minakshi Dongre3Sankalp Arora4Dept. of Pharmacology & Therapeutics, Seth GS Medical College & KEM Hospital, Parel, Mumbai 400012, India; Corresponding author.Dept. of Pharmacology & Therapeutics, Seth GS Medical College & KEM Hospital, Parel, Mumbai 400012, IndiaDept. of Anaesthesiology, Seth GS Medical College & KEM Hospital, Parel, Mumbai 400012, IndiaDept. of Pharmacology & Therapeutics, Seth GS Medical College & KEM Hospital, Parel, Mumbai 400012, IndiaSeth GS Medical College & KEM Hospital, Parel, Mumbai 400012, IndiaIntroduction: Hypertension is regarded as an additional risk factor during anaesthesia. There is not enough Indian evidence in literature regarding antihypertensive usage and its implications during perioperative period in patients undergoing general & orthopedic surgery. This drove us to conduct this study. Methods: Single centre cross-sectional observational study conducted in a General Surgery and Orthopaedics wards of a Tertiary care hospital. The data was collected from the period of first visit by the anaesthetist to 24 h’ postoperative period of the operated hypertensive patients. The variables accounted were of antihypertensive medications, anaesthesia drugs, hemodynamics, blood loss and fluids used. The data was analysed by using descriptive statistics, nonparametric tests and P < 0.05 was considered as significant. Results: 180 patients had median age of 65 years (Interquartile range – 20). Calcium channel Blockers were the most common class and Amlodipine was most common antihypertensive medication used during perioperative period. 132 patients took antihypertensive medication on the morning of the surgery. In 136 patients’ antihypertensive medication was started within 24 h’ postoperative period. Bupivacaine was most common anaesthetic drug used. Intraoperative fall in SBP (Systolic Blood Pressure) was found in 31 patients, and rises were found in 7 patients. Also, intraoperative fall in DBP (Diastolic Blood Pressure) was found in 13 patients, and rises were found in 9 patients. Intraoperative hemodynamic changes were managed appropriately by the anaesthetist. The median IV fluids given intraoperatively was 1375 ml (Interquartile range – 700). Median blood loss was 272 ml (Interquartile range – 250). Conclusion: Antihypertensive medications use during perioperative period were not associated with major hemodynamic changes. Keywords: General surgery, Orthopaedics, Hemodynamicshttp://www.sciencedirect.com/science/article/pii/S1110184917303318
collection DOAJ
language English
format Article
sources DOAJ
author Paresh Girdharlal Koli
Yashashri Shetty
Sweta Salgaonkar
Minakshi Dongre
Sankalp Arora
spellingShingle Paresh Girdharlal Koli
Yashashri Shetty
Sweta Salgaonkar
Minakshi Dongre
Sankalp Arora
Cross-sectional study about perioperative management of Blood Pressure and effects of anaesthesia in hypertensive patients undergoing general & orthopaedic surgery
Egyptian Journal of Anaesthesia
author_facet Paresh Girdharlal Koli
Yashashri Shetty
Sweta Salgaonkar
Minakshi Dongre
Sankalp Arora
author_sort Paresh Girdharlal Koli
title Cross-sectional study about perioperative management of Blood Pressure and effects of anaesthesia in hypertensive patients undergoing general & orthopaedic surgery
title_short Cross-sectional study about perioperative management of Blood Pressure and effects of anaesthesia in hypertensive patients undergoing general & orthopaedic surgery
title_full Cross-sectional study about perioperative management of Blood Pressure and effects of anaesthesia in hypertensive patients undergoing general & orthopaedic surgery
title_fullStr Cross-sectional study about perioperative management of Blood Pressure and effects of anaesthesia in hypertensive patients undergoing general & orthopaedic surgery
title_full_unstemmed Cross-sectional study about perioperative management of Blood Pressure and effects of anaesthesia in hypertensive patients undergoing general & orthopaedic surgery
title_sort cross-sectional study about perioperative management of blood pressure and effects of anaesthesia in hypertensive patients undergoing general & orthopaedic surgery
publisher Taylor & Francis Group
series Egyptian Journal of Anaesthesia
issn 1110-1849
publishDate 2018-07-01
description Introduction: Hypertension is regarded as an additional risk factor during anaesthesia. There is not enough Indian evidence in literature regarding antihypertensive usage and its implications during perioperative period in patients undergoing general & orthopedic surgery. This drove us to conduct this study. Methods: Single centre cross-sectional observational study conducted in a General Surgery and Orthopaedics wards of a Tertiary care hospital. The data was collected from the period of first visit by the anaesthetist to 24 h’ postoperative period of the operated hypertensive patients. The variables accounted were of antihypertensive medications, anaesthesia drugs, hemodynamics, blood loss and fluids used. The data was analysed by using descriptive statistics, nonparametric tests and P < 0.05 was considered as significant. Results: 180 patients had median age of 65 years (Interquartile range – 20). Calcium channel Blockers were the most common class and Amlodipine was most common antihypertensive medication used during perioperative period. 132 patients took antihypertensive medication on the morning of the surgery. In 136 patients’ antihypertensive medication was started within 24 h’ postoperative period. Bupivacaine was most common anaesthetic drug used. Intraoperative fall in SBP (Systolic Blood Pressure) was found in 31 patients, and rises were found in 7 patients. Also, intraoperative fall in DBP (Diastolic Blood Pressure) was found in 13 patients, and rises were found in 9 patients. Intraoperative hemodynamic changes were managed appropriately by the anaesthetist. The median IV fluids given intraoperatively was 1375 ml (Interquartile range – 700). Median blood loss was 272 ml (Interquartile range – 250). Conclusion: Antihypertensive medications use during perioperative period were not associated with major hemodynamic changes. Keywords: General surgery, Orthopaedics, Hemodynamics
url http://www.sciencedirect.com/science/article/pii/S1110184917303318
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