Protocadherins at the Crossroad of Signaling Pathways

Protocadherins at the Crossroad of Signaling Pathways

Protocadherins (Pcdhs) are cell adhesion molecules that belong to the cadherin superfamily, and are subdivided into clustered (cPcdhs) and non-clustered Pcdhs (ncPcdhs) in vertebrates. In this review, we summarize their discovery, expression mechanisms, and roles in neuronal development and cancer,...

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Bibliographic Details
Main Authors: Anna Pancho, Tania Aerts, Manuela D. Mitsogiannis, Eve Seuntjens
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Molecular Neuroscience
Subjects:
clustered protocadherin
non-clustered protocadherin
WAVE
Wnt
apoptosis
cell adhesion
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2020.00117/full

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