Locoregional ablative treatment of melanoma metastases
Standard treatment of melanoma has been evolving rapidly over the last decade, with novel treatment approaches improving therapeutic outcome not only in early-stage disease but also in advanced stage metastatic patients. Despite the improvement of systemic therapy outcomes, the current treatment gui...
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Online Access: | http://dx.doi.org/10.1080/02656736.2019.1647353 |
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doaj-376befab62704233b6010553a1ae56812020-11-24T20:43:07ZengTaylor & Francis GroupInternational Journal of Hyperthermia0265-67361464-51572019-10-01362596310.1080/02656736.2019.16473531647353Locoregional ablative treatment of melanoma metastasesDaniel Putzer0Peter Schullian1Reto Bale2Medical University InnsbruckMedical University InnsbruckMedical University InnsbruckStandard treatment of melanoma has been evolving rapidly over the last decade, with novel treatment approaches improving therapeutic outcome not only in early-stage disease but also in advanced stage metastatic patients. Despite the improvement of systemic therapy outcomes, the current treatment guidelines reflect the fact that locoregional treatment approaches can be beneficial in patients suffering from oligometastatic disease. Minimally invasive ablation techniques have been established as a therapeutic cornerstone in the management of liver tumors, representing a local curative, relatively low-risk procedure. Depending on the size and location of metastatic disease, and on the applied ablation and guidance technique, ablative treatment approaches are effective to treat metastases in solid organs such as the liver or lungs, effectively covering the entire tumor with the ablation zone including a safety margin (A0 ablation in analogy to R0 resection). However, only retrospective data and case reports on locoregional treatment of melanoma metastases are available up to now, and prospective evaluation of this therapeutic approach is warranted to evaluate the beneficial role in the treatment of metastatic melanoma patients.http://dx.doi.org/10.1080/02656736.2019.1647353Radiofrequency ablationliver tumor treatmentpercutaneous tumor treatmentinterventional oncologyminimally invasive oncology |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Daniel Putzer Peter Schullian Reto Bale |
spellingShingle |
Daniel Putzer Peter Schullian Reto Bale Locoregional ablative treatment of melanoma metastases International Journal of Hyperthermia Radiofrequency ablation liver tumor treatment percutaneous tumor treatment interventional oncology minimally invasive oncology |
author_facet |
Daniel Putzer Peter Schullian Reto Bale |
author_sort |
Daniel Putzer |
title |
Locoregional ablative treatment of melanoma metastases |
title_short |
Locoregional ablative treatment of melanoma metastases |
title_full |
Locoregional ablative treatment of melanoma metastases |
title_fullStr |
Locoregional ablative treatment of melanoma metastases |
title_full_unstemmed |
Locoregional ablative treatment of melanoma metastases |
title_sort |
locoregional ablative treatment of melanoma metastases |
publisher |
Taylor & Francis Group |
series |
International Journal of Hyperthermia |
issn |
0265-6736 1464-5157 |
publishDate |
2019-10-01 |
description |
Standard treatment of melanoma has been evolving rapidly over the last decade, with novel treatment approaches improving therapeutic outcome not only in early-stage disease but also in advanced stage metastatic patients. Despite the improvement of systemic therapy outcomes, the current treatment guidelines reflect the fact that locoregional treatment approaches can be beneficial in patients suffering from oligometastatic disease. Minimally invasive ablation techniques have been established as a therapeutic cornerstone in the management of liver tumors, representing a local curative, relatively low-risk procedure. Depending on the size and location of metastatic disease, and on the applied ablation and guidance technique, ablative treatment approaches are effective to treat metastases in solid organs such as the liver or lungs, effectively covering the entire tumor with the ablation zone including a safety margin (A0 ablation in analogy to R0 resection). However, only retrospective data and case reports on locoregional treatment of melanoma metastases are available up to now, and prospective evaluation of this therapeutic approach is warranted to evaluate the beneficial role in the treatment of metastatic melanoma patients. |
topic |
Radiofrequency ablation liver tumor treatment percutaneous tumor treatment interventional oncology minimally invasive oncology |
url |
http://dx.doi.org/10.1080/02656736.2019.1647353 |
work_keys_str_mv |
AT danielputzer locoregionalablativetreatmentofmelanomametastases AT peterschullian locoregionalablativetreatmentofmelanomametastases AT retobale locoregionalablativetreatmentofmelanomametastases |
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1716820494694481920 |