Seropositivity of Transfusion Transmitted Infections among Blood Donors in Hilly Region of Karnataka, India
Introduction: One of the major problem associated with blood transfusions are Transfusion Transmitted Infections (TTIs). Accurate estimates of risk of TTIs are essential for monitoring the safety of blood supply. National AIDS Control Organisation (NACO) guidelines state that all donor’s blood s...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
JCDR Research and Publications Pvt. Ltd.
2021-04-01
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Series: | National Journal of Laboratory Medicine |
Subjects: | |
Online Access: | http://www.njlm.net/articles/PDF/2460/45632_CE[Ra1]_F(SHU)_PF1(AG_SHU)_PFA(SHU)_PB(AG_SHU)_PN(SHU).pdf |
Summary: | Introduction: One of the major problem associated with blood
transfusions are Transfusion Transmitted Infections (TTIs).
Accurate estimates of risk of TTIs are essential for monitoring the
safety of blood supply. National AIDS Control Organisation (NACO)
guidelines state that all donor’s blood samples should mandatorily
be tested for Human Immunodeficiency Virus (HIV), Hepatitis B
Virus (HBV), Hepatitis C Virus (HCV), Syphilis and Malaria.
Aim: To estimate the seropositivity of HIV, Hepatitis B surface
Antigen (HBsAg), HCV, Syphilis and Malaria among blood donors
for tertiary care hospital of hilly region in Karnataka, India.
Materials and Methods: This cross-sectional study was done
from January 2012 to March 2018 in District Hospital Blood
bank, Department of Pathology, Kodagu Institute of Medical
Sciences, Madikeri, Karnataka, India. The blood donors were
screened with detailed history and physical examination
according to Standard Operating Procedures (SOP) of Blood
bank as per Guidelines for Blood donor selection and referral.
Donor blood sample was subjected to screening investigations
for TTIs diseases: HIV, HBV, HCV, Syphilis and Malaria. Data
collected was tabulated in Microscoft Excel and results were
expressed as percentage.
Results: The study included total 9599 blood donors. The total
number of male donors was 8985 and female donors were 614.
There were 74 seropositive donors of which 71 (96%) were males
and 3 (4.0%) were females. The total seropositivity rate of TTIs was
0.77% among which the incidence of seropositivity was higher in
males as compared to females. There were 55 donors (0.58%)
positive for HBV, eight donors (0.08%) positive for Syphilis, five
donors (0.05%) positive for HIV, four donors (0.04%) positive for
Malaria and two donors (0.02%) positive for HCV.
Conclusion: Screening and better selection of donors by
testing for TTIs are necessary to improve blood safety in the
blood transfusion centre of hospital. |
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ISSN: | 2277-8551 2455-6882 |