Dietary Intake of Protein from Different Sources and Weight Regain, Changes in Body Composition and Cardiometabolic Risk Factors after Weight Loss: The DIOGenes Study
An increase in dietary protein intake has been shown to improve weight loss maintenance in the DIOGenes trial. Here, we analysed whether the source of the dietary proteins influenced changes in body weight, body composition, and cardiometabolic risk factors during the weight maintenance period while...
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doaj-3788744eb0ac4e548fdb870fcc89857d2020-11-24T21:18:32ZengMDPI AGNutrients2072-66432017-12-01912132610.3390/nu9121326nu9121326Dietary Intake of Protein from Different Sources and Weight Regain, Changes in Body Composition and Cardiometabolic Risk Factors after Weight Loss: The DIOGenes StudyMarleen A. van Baak0Thomas M. Larsen1Susan A. Jebb2Alfredo Martinez3Wim H. M. Saris4Teodora Handjieva-Darlenska5Anthony Kafatos6Andreas F. H. Pfeiffer7Marie Kunešová8Arne Astrup9Department of Human Biology, NUTRIM School for Nutrition and Translational Research in Metabolism, Maastricht University Medical Centre, 6200MD Maastricht, The NetherlandsDepartment of Nutrition, Exercise and Sports (NEXS), Faculty of Science, University of Copenhagen, 2200 Copenhagen, DenmarkNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford OX2 6GG, UKDepartment of Physiology and Nutrition, University of Navarra, 31008 Pamplona, SpainDepartment of Human Biology, NUTRIM School for Nutrition and Translational Research in Metabolism, Maastricht University Medical Centre, 6200MD Maastricht, The NetherlandsDepartment of Pharmacology and Toxicology, Faculty of Medicine, Medical University, 1000 Sofia, BulgariaDepartment of Social Medicine, Preventive Medicine & Nutrition Clinic, University of Crete, 71003 Heraklion, GreeceDepartment of Clinical Nutrition, German Institute of Human Nutrition Potsdam-Rehbrücke, 14558 Nuthetal, GermanyObesity Management Center, Institute of Endocrinology, 11694 Prague, Czech RepublicDepartment of Nutrition, Exercise and Sports (NEXS), Faculty of Science, University of Copenhagen, 2200 Copenhagen, DenmarkAn increase in dietary protein intake has been shown to improve weight loss maintenance in the DIOGenes trial. Here, we analysed whether the source of the dietary proteins influenced changes in body weight, body composition, and cardiometabolic risk factors during the weight maintenance period while following an energy-restricted diet. 489 overweight or obese participants of the DIOGenes trial from eight European countries were included. They successfully lost >8% of body weight and subsequently completed a six month weight maintenance period, in which they consumed an ad libitum diet varying in protein content and glycemic index. Dietary intake was estimated from three-day food diaries. A higher plant protein intake with a proportional decrease in animal protein intake did not affect body weight maintenance or cardiometabolic risk factors. A higher plant protein intake from non-cereal products instead of cereal products was associated with benefits for body weight maintenance and blood pressure. Substituting meat protein for protein from other animal sources increased insulin and HOMA-IR (homeostasis model assessment of insulin resistance). This analysis suggests that not only the amount of dietary proteins, but also the source may be important for weight and cardiometabolic risk management. However, randomized trials are needed to test the causality of these associations.https://www.mdpi.com/2072-6643/9/12/1326weight loss maintenancedietprotein sourcescardiometabolic risk factorsobesityplant proteinanimal proteinmeat proteincereal protein |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Marleen A. van Baak Thomas M. Larsen Susan A. Jebb Alfredo Martinez Wim H. M. Saris Teodora Handjieva-Darlenska Anthony Kafatos Andreas F. H. Pfeiffer Marie Kunešová Arne Astrup |
spellingShingle |
Marleen A. van Baak Thomas M. Larsen Susan A. Jebb Alfredo Martinez Wim H. M. Saris Teodora Handjieva-Darlenska Anthony Kafatos Andreas F. H. Pfeiffer Marie Kunešová Arne Astrup Dietary Intake of Protein from Different Sources and Weight Regain, Changes in Body Composition and Cardiometabolic Risk Factors after Weight Loss: The DIOGenes Study Nutrients weight loss maintenance diet protein sources cardiometabolic risk factors obesity plant protein animal protein meat protein cereal protein |
author_facet |
Marleen A. van Baak Thomas M. Larsen Susan A. Jebb Alfredo Martinez Wim H. M. Saris Teodora Handjieva-Darlenska Anthony Kafatos Andreas F. H. Pfeiffer Marie Kunešová Arne Astrup |
author_sort |
Marleen A. van Baak |
title |
Dietary Intake of Protein from Different Sources and Weight Regain, Changes in Body Composition and Cardiometabolic Risk Factors after Weight Loss: The DIOGenes Study |
title_short |
Dietary Intake of Protein from Different Sources and Weight Regain, Changes in Body Composition and Cardiometabolic Risk Factors after Weight Loss: The DIOGenes Study |
title_full |
Dietary Intake of Protein from Different Sources and Weight Regain, Changes in Body Composition and Cardiometabolic Risk Factors after Weight Loss: The DIOGenes Study |
title_fullStr |
Dietary Intake of Protein from Different Sources and Weight Regain, Changes in Body Composition and Cardiometabolic Risk Factors after Weight Loss: The DIOGenes Study |
title_full_unstemmed |
Dietary Intake of Protein from Different Sources and Weight Regain, Changes in Body Composition and Cardiometabolic Risk Factors after Weight Loss: The DIOGenes Study |
title_sort |
dietary intake of protein from different sources and weight regain, changes in body composition and cardiometabolic risk factors after weight loss: the diogenes study |
publisher |
MDPI AG |
series |
Nutrients |
issn |
2072-6643 |
publishDate |
2017-12-01 |
description |
An increase in dietary protein intake has been shown to improve weight loss maintenance in the DIOGenes trial. Here, we analysed whether the source of the dietary proteins influenced changes in body weight, body composition, and cardiometabolic risk factors during the weight maintenance period while following an energy-restricted diet. 489 overweight or obese participants of the DIOGenes trial from eight European countries were included. They successfully lost >8% of body weight and subsequently completed a six month weight maintenance period, in which they consumed an ad libitum diet varying in protein content and glycemic index. Dietary intake was estimated from three-day food diaries. A higher plant protein intake with a proportional decrease in animal protein intake did not affect body weight maintenance or cardiometabolic risk factors. A higher plant protein intake from non-cereal products instead of cereal products was associated with benefits for body weight maintenance and blood pressure. Substituting meat protein for protein from other animal sources increased insulin and HOMA-IR (homeostasis model assessment of insulin resistance). This analysis suggests that not only the amount of dietary proteins, but also the source may be important for weight and cardiometabolic risk management. However, randomized trials are needed to test the causality of these associations. |
topic |
weight loss maintenance diet protein sources cardiometabolic risk factors obesity plant protein animal protein meat protein cereal protein |
url |
https://www.mdpi.com/2072-6643/9/12/1326 |
work_keys_str_mv |
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