Pulmonary arterial hypertension and flavonoids: A role in treatment
Pulmonary arterial hypertension (PAH) is a high mortality progressive pulmonary vascular disease that can lead to right heart failure. The use of clinical drugs for the treatment of PAH is limited to a great extent because of its single target and high price. Flavonoids are widely distributed in nat...
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Wolters Kluwer Medknow Publications
2021-01-01
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doaj-378e18990c4a4546a15a5e014b97d7c02021-07-07T10:31:31ZengWolters Kluwer Medknow PublicationsChinese Journal of Physiology0304-49202666-00592021-01-0164311512410.4103/cjp.cjp_25_21Pulmonary arterial hypertension and flavonoids: A role in treatmentJialing WangHailong LiTian XiaJun FengRu ZhouPulmonary arterial hypertension (PAH) is a high mortality progressive pulmonary vascular disease that can lead to right heart failure. The use of clinical drugs for the treatment of PAH is limited to a great extent because of its single target and high price. Flavonoids are widely distributed in nature, and have been found in fruits, vegetables, and traditional Chinese medicine. They have diverse biological activities and various pharmacological effects such as antitumor, antioxidation, and anti-inflammatory. This review summarizes the progress in pharmacodynamics and mechanism of flavonoids in the treatment of PAH in recent years, in order to provide some theoretical references for relevant researchers.http://www.cjphysiology.org/article.asp?issn=0304-4920;year=2021;volume=64;issue=3;spage=115;epage=124;aulast=Wangflavonoidspulmonary arterial hypertensiontreatment |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Jialing Wang Hailong Li Tian Xia Jun Feng Ru Zhou |
spellingShingle |
Jialing Wang Hailong Li Tian Xia Jun Feng Ru Zhou Pulmonary arterial hypertension and flavonoids: A role in treatment Chinese Journal of Physiology flavonoids pulmonary arterial hypertension treatment |
author_facet |
Jialing Wang Hailong Li Tian Xia Jun Feng Ru Zhou |
author_sort |
Jialing Wang |
title |
Pulmonary arterial hypertension and flavonoids: A role in treatment |
title_short |
Pulmonary arterial hypertension and flavonoids: A role in treatment |
title_full |
Pulmonary arterial hypertension and flavonoids: A role in treatment |
title_fullStr |
Pulmonary arterial hypertension and flavonoids: A role in treatment |
title_full_unstemmed |
Pulmonary arterial hypertension and flavonoids: A role in treatment |
title_sort |
pulmonary arterial hypertension and flavonoids: a role in treatment |
publisher |
Wolters Kluwer Medknow Publications |
series |
Chinese Journal of Physiology |
issn |
0304-4920 2666-0059 |
publishDate |
2021-01-01 |
description |
Pulmonary arterial hypertension (PAH) is a high mortality progressive pulmonary vascular disease that can lead to right heart failure. The use of clinical drugs for the treatment of PAH is limited to a great extent because of its single target and high price. Flavonoids are widely distributed in nature, and have been found in fruits, vegetables, and traditional Chinese medicine. They have diverse biological activities and various pharmacological effects such as antitumor, antioxidation, and anti-inflammatory. This review summarizes the progress in pharmacodynamics and mechanism of flavonoids in the treatment of PAH in recent years, in order to provide some theoretical references for relevant researchers. |
topic |
flavonoids pulmonary arterial hypertension treatment |
url |
http://www.cjphysiology.org/article.asp?issn=0304-4920;year=2021;volume=64;issue=3;spage=115;epage=124;aulast=Wang |
work_keys_str_mv |
AT jialingwang pulmonaryarterialhypertensionandflavonoidsaroleintreatment AT hailongli pulmonaryarterialhypertensionandflavonoidsaroleintreatment AT tianxia pulmonaryarterialhypertensionandflavonoidsaroleintreatment AT junfeng pulmonaryarterialhypertensionandflavonoidsaroleintreatment AT ruzhou pulmonaryarterialhypertensionandflavonoidsaroleintreatment |
_version_ |
1721316474701742080 |