The MRC1/CD68 ratio is positively associated with adipose tissue lipogenesis and with muscle mitochondrial gene expression in humans.

The MRC1/CD68 ratio is positively associated with adipose tissue lipogenesis and with muscle mitochondrial gene expression in humans.

BACKGROUND: Alternative macrophages (M2) express the cluster differentiation (CD) 206 (MCR1) at high levels. Decreased M2 in adipose tissue is known to be associated with obesity and inflammation-related metabolic disturbances. Here we aimed to investigate MCR1 relative to CD68 (total macrophages) g...

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Bibliographic Details
Main Authors: José María Moreno-Navarrete, Francisco Ortega, María Gómez-Serrano, Eva García-Santos, Wifredo Ricart, Francisco Tinahones, Geltrude Mingrone, Belén Peral, José Manuel Fernández-Real
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3741275?pdf=render

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