Reconstitution of intestinal CD4 and Th17 T cells in antiretroviral therapy suppressed HIV-infected subjects: implication for residual immune activation from the results of a clinical trial.

Reconstitution of intestinal CD4 and Th17 T cells in antiretroviral therapy suppressed HIV-infected subjects: implication for residual immune activation from the results of a clinical trial.

During HIV infection the severe depletion of intestinal CD4+ T-cells is associated with microbial translocation, systemic immune activation, and disease progression. This study examined intestinal and peripheral CD4+ T-cell subsets reconstitution under combined antiretroviral therapy (cART), and sys...

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Bibliographic Details
Main Authors: Gabriella d'Ettorre, Silvia Baroncelli, Luca Micci, Giancarlo Ceccarelli, Mauro Andreotti, Prachi Sharma, Gianfranco Fanello, Fausto Fiocca, Eugenio Nelson Cavallari, Noemi Giustini, Alessandra Mallano, Clementina M Galluzzo, Stefano Vella, Claudio M Mastroianni, Guido Silvestri, Mirko Paiardini, Vincenzo Vullo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4207675?pdf=render

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http://europepmc.org/articles/PMC4207675?pdf=render

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