Synthesis and In Vitro Evaluation of Gold Nanoparticles Functionalized with Thiol Ligands for Robust Radiolabeling with <sup>99m</sup>Tc

Synthesis and In Vitro Evaluation of Gold Nanoparticles Functionalized with Thiol Ligands for Robust Radiolabeling with <sup>99m</sup>Tc

Radiolabeled gold nanoparticles (AuNPs) have been widely used for cancer diagnosis and therapy over recent decades. In this study, we focused on the development and in vitro evaluation of four new Au nanoconjugates radiolabeled with technetium-99m (<sup>99m</sup>Tc) via thiol-bearing lig...

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Main Authors: Adamantia Apostolopoulou, Aristeidis Chiotellis, Evangelia-Alexandra Salvanou, Konstantina Makrypidi, Charalampos Tsoukalas, Fotis Kapiris, Maria Paravatou-Petsotas, Minas Papadopoulos, Ioannis C. Pirmettis, Przemysław Koźmiński, Penelope Bouziotis
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Nanomaterials
Subjects:
gold nanoparticles
<sup>99m</sup>Tc-carbonyls
radiolabeling
cytotoxicity
MTT
hemolysis assay
Online Access:https://www.mdpi.com/2079-4991/11/9/2406

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