Study of relationship between QTC prolongation and cardiac autonomic neuropathy in Diabetes mellitus
Objective: Cardiac Autonomic neuropathy is one of the complications in diabetic patients. This study intends to detect the prevalence of QTc prolongation in diabetic patients as well as its relationship with cardiac autonomic neuropathy. Materials & Methods: The present study was conducted...
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| Format: | Article |
| Language: | English |
| Published: |
Prathima Institute of Medical Sciences
2017-12-01
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| Series: | Perspectives In Medical Research |
| Subjects: | |
| Online Access: | http://www.pimr.org.in/natarajan_vol5-issue3-2017.PDF |
| Summary: | Objective: Cardiac Autonomic neuropathy is one of the
complications in diabetic patients. This study intends to detect
the prevalence of QTc prolongation in diabetic patients as well
as its relationship with cardiac autonomic neuropathy.
Materials & Methods: The present study was
conducted on 50 diabetic patients. Cardiac autonomic
neuropathy was assessed by non-invasive tests: Deep breathing
test, Valsalva ratio ,Immediate heart rate response to standing
30:15,B.P rise with sustained hand grip and postural
hypotension. Scoring and grading were done for cardiac
autonomic neuropathy . Even QT interval and QTc interval were
determined.
Results: Out of 50 diabetic patients, 22(44%) were
males and 28 (56%) females. 26 patients (52%) having grade I
cardiac autonomic neuropathy had no prolonged QTc interval
. While, 24 patients (48%) had QTc prolonged were associated
with grade II, III and IV cardiac autonomic neuropathy. The
sensitivity and specificity of prolonged QTc were 46% and
100%, respectively.
Conclusion: QTc prolongation correlated positivity with
degree of cardiac autonomic neuropathy in diabetic patients |
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| ISSN: | 2348-1447 2348-229X |