In-vivo application of low frequency alternating currents on porcine cervical vagus nerve evokes reversible nerve conduction block

In-vivo application of low frequency alternating currents on porcine cervical vagus nerve evokes reversible nerve conduction block

Abstract Background This paper describes a method to reversibly block nerve conduction through direct application of a 1 Hz sinusoidal current waveform delivered through a bipolar nerve cuff electrode. This low frequency alternating current (LFAC) waveform was previously shown to reversibly block th...

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Bibliographic Details
Main Authors: Maria Ivette Muzquiz, Lindsay Richardson, Christian Vetter, Macallister Smolik, Awadh Alhawwash, Adam Goodwill, Rizwan Bashirullah, Michael Carr, Ken Yoshida
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Bioelectronic Medicine
Subjects:
Neuromodulation
Conduction block
Nerve block
Low frequency alternating current block
Online Access:https://doi.org/10.1186/s42234-021-00072-w

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