Association of CD28 IVS3 +17T/C Polymorphism with Soluble CD28 in Rheumatoid Arthritis

Objective: Rheumatoid arthritis (RA) is an autoimmune disease of unknown etiology in which inflammatory pathology involves T cell activation and the CD28 costimulatory molecule involved in T cell presentation. The gene includes the CD28 IVS3 +17T/C polymorphism that could be associated with suscepti...

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Main Authors: I. Y. Ledezma-Lozano, J. J. Padilla-Martínez, S. D. Leyva-Torres, I. Parra-Rojas, M. G. Ramírez-Dueñas, Ana Laura Pereira-Suárez, H. Rangel-Villalobos, S. L. Ruiz-Quezada, P. E. Sánchez-Hernández, J. F. Muñoz-Valle
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:Disease Markers
Online Access:http://dx.doi.org/10.3233/DMA-2011-0760