Persistent Polyclonal B Cell Lymphocytosis B Cells Can Be Activated through CD40-CD154 Interaction

Persistent polyclonal B cell lymphocytosis (PPBL) is a rare disorder, diagnosed primarily in adult female smokers and characterized by an expansion of CD19+CD27+IgM+ memory B cells, by the presence of binucleated lymphocytes, and by a moderate elevation of serum IgM. The clinical course is usually b...

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Bibliographic Details
Main Authors: Emmanuelle Dugas-Bourdages, Sonia Néron, Annie Roy, André Darveau, Robert Delage
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:Advances in Hematology
Online Access:http://dx.doi.org/10.1155/2014/854124

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