Persistent Polyclonal B Cell Lymphocytosis B Cells Can Be Activated through CD40-CD154 Interaction
Persistent polyclonal B cell lymphocytosis (PPBL) is a rare disorder, diagnosed primarily in adult female smokers and characterized by an expansion of CD19+CD27+IgM+ memory B cells, by the presence of binucleated lymphocytes, and by a moderate elevation of serum IgM. The clinical course is usually b...
Main Authors: | Emmanuelle Dugas-Bourdages, Sonia Néron, Annie Roy, André Darveau, Robert Delage |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2014-01-01
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Series: | Advances in Hematology |
Online Access: | http://dx.doi.org/10.1155/2014/854124 |
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