Lipids and All-Cause Mortality among Older Adults: A 12-Year Follow-Up Study
This is a 12-year follow-up cohort study with 800 people (60–85 years old). The association between lipid disorders and mortality was analysed by Cox proportional hazard adjusted model. All-cause mortality was considered the dependent variable, and lipid disorders as independent variables: total cho...
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doaj-3843a8d273bf42179e76050893a69cf92020-11-25T00:50:37ZengHindawi LimitedThe Scientific World Journal1537-744X2012-01-01201210.1100/2012/930139930139Lipids and All-Cause Mortality among Older Adults: A 12-Year Follow-Up StudyMarcos Aparecido Sarria Cabrera0Selma Maffei de Andrade1Renata Maciulis Dip2Discipline of Geriatrics, Postgraduate Program in Public Health, State University of Londrina (UEL), Robert Koch Avenue, 60 CEP, 86038440 Londrina, PR, BrazilDepartment of Public Health, Postgraduate Program in Public Health, State University of Londrina (UEL), Robert Koch Avenue, 60 CEP, 86038440 Londrina, PR, BrazilDiscipline of Geriatrics, Postgraduate Program in Public Health, State University of Londrina (UEL), Robert Koch Avenue, 60 CEP, 86038440 Londrina, PR, BrazilThis is a 12-year follow-up cohort study with 800 people (60–85 years old). The association between lipid disorders and mortality was analysed by Cox proportional hazard adjusted model. All-cause mortality was considered the dependent variable, and lipid disorders as independent variables: total cholesterol (TC) >200 and <170 mg/dl, HDL-c <35 and 40, LDL-c >100 and 130, and triglycerides (TG) >50. An initial analysis of all subjects was performed and a second was carried out after having excluded individuals with a body mass index (BMI) <20 kg/m2 or mortality in ≤2 years. The mortality showed a positive association with low TC and a negative association with high TC and high LDL-c. After the exclusion of underweight and premature mortality, there was a positive association only with TC <170 mg/dl (HR = 1.36, CI95%: 1.02–1.82). The data did not show a higher risk with high levels of TC, LDL-c, and TG. However, they showed higher mortality among older adults with low TC.http://dx.doi.org/10.1100/2012/930139 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Marcos Aparecido Sarria Cabrera Selma Maffei de Andrade Renata Maciulis Dip |
spellingShingle |
Marcos Aparecido Sarria Cabrera Selma Maffei de Andrade Renata Maciulis Dip Lipids and All-Cause Mortality among Older Adults: A 12-Year Follow-Up Study The Scientific World Journal |
author_facet |
Marcos Aparecido Sarria Cabrera Selma Maffei de Andrade Renata Maciulis Dip |
author_sort |
Marcos Aparecido Sarria Cabrera |
title |
Lipids and All-Cause Mortality among Older Adults: A 12-Year Follow-Up Study |
title_short |
Lipids and All-Cause Mortality among Older Adults: A 12-Year Follow-Up Study |
title_full |
Lipids and All-Cause Mortality among Older Adults: A 12-Year Follow-Up Study |
title_fullStr |
Lipids and All-Cause Mortality among Older Adults: A 12-Year Follow-Up Study |
title_full_unstemmed |
Lipids and All-Cause Mortality among Older Adults: A 12-Year Follow-Up Study |
title_sort |
lipids and all-cause mortality among older adults: a 12-year follow-up study |
publisher |
Hindawi Limited |
series |
The Scientific World Journal |
issn |
1537-744X |
publishDate |
2012-01-01 |
description |
This is a 12-year follow-up cohort study with 800 people (60–85 years old). The association between lipid disorders and mortality was analysed by Cox proportional hazard adjusted model. All-cause mortality was considered the dependent variable, and lipid disorders as independent variables: total cholesterol (TC) >200 and <170 mg/dl, HDL-c <35 and 40, LDL-c >100 and 130, and triglycerides (TG) >50. An initial analysis of all subjects was performed and a second was carried out after having excluded individuals with a body mass index (BMI) <20 kg/m2 or mortality in ≤2 years. The mortality showed a positive association with low TC and a negative association with high TC and high LDL-c. After the exclusion of underweight and premature mortality, there was a positive association only with TC <170 mg/dl (HR = 1.36, CI95%: 1.02–1.82). The data did not show a higher risk with high levels of TC, LDL-c, and TG. However, they showed higher mortality among older adults with low TC. |
url |
http://dx.doi.org/10.1100/2012/930139 |
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