Optimal <it>ex vivo </it>expansion of neutrophils from PBSC CD34<sup>+ </sup>cells by a combination of SCF, Flt3-L and G-CSF and its inhibition by further addition of TPO
<p>Abstract</p> <p>Background</p> <p>Autologous mobilised peripheral blood stem cell (PBSC) transplantation is now a standard approach in the treatment of haematological diseases to reconstitute haematopoiesis following myeloablative chemotherapy. However, there remains...
Main Authors: | Turner Marc L, Davies John, Roddie Huw, Barclay G Robin, Tura Olga |
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Format: | Article |
Language: | English |
Published: |
BMC
2007-10-01
|
Series: | Journal of Translational Medicine |
Online Access: | http://www.translational-medicine.com/content/5/1/53 |
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