NOSOTROPIC SUBSTANTIATION OF ANTI IgE ANIBODY THERAPY

This article studies the specifics of allergic diseases pathogenesis. Such common allergic diseases as bronchial asthma, allergic rhinitis and atopic dermatitis are conditioned by processes based on increase of immunoglobulin e synthesis. Omalizunab, which is a recombinant humanized monoclone anti-I...

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Bibliographic Details
Main Author: Yu.G. Levina
Format: Article
Language:English
Published: Paediatrician Publishers, LLC 2008-03-01
Series:Pediatričeskaâ Farmakologiâ
Online Access:https://pf.spr-journal.ru/jour/article/view/875
Description
Summary:This article studies the specifics of allergic diseases pathogenesis. Such common allergic diseases as bronchial asthma, allergic rhinitis and atopic dermatitis are conditioned by processes based on increase of immunoglobulin e synthesis. Omalizunab, which is a recombinant humanized monoclone anti-Ige antibody, prevents Ige fixing to membrane receptors of mast cells and significantly reduces the level of immunoglobulin e circulating in blood.Key words: anti-Ige antibody, omalizumab, allergic diseases, Bronchial asthma, children.
ISSN:1727-5776
2500-3089