Incidental diagnosis of sternoclavicular septic arthritis with Moraxella nonliquefaciens

An 83-year old man presented acutely to the emergency department with generalized weakness and subjective fevers. A month earlier he had undergone resection of a large intramuscular sarcoma from his thigh. The cancer staging work-up was still underway and a decision about adjuvant therapy was still...

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Main Authors: Ehab Saad Aldin, Poorani Sekar, Zein Saad Eddin, Jaclyn Keller, Janet Pollard
Format: Article
Language:English
Published: Elsevier 2018-01-01
Series:IDCases
Online Access:http://www.sciencedirect.com/science/article/pii/S2214250918300465
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spelling doaj-38858622affa458bb33ace2de060067d2021-07-02T11:41:15ZengElsevierIDCases2214-25092018-01-01124446Incidental diagnosis of sternoclavicular septic arthritis with Moraxella nonliquefaciensEhab Saad Aldin0Poorani Sekar1Zein Saad Eddin2Jaclyn Keller3Janet Pollard4Department of Diagnostic Radiology, University of Iowa Hospitals and Clinics, Iowa City, IA 52242, United States; Corresponding author at: Department of Diagnostic Radiology—Division of Nuclear Medicine, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, Iowa City, IA 52242, United States.Department of Internal Medicine, University of Iowa Hospitals and Clinics, Iowa City, IA 52242, United StatesDepartment of Vascular Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, United StatesDepartment of Diagnostic Radiology, University of Iowa Hospitals and Clinics, Iowa City, IA 52242, United StatesDepartment of Diagnostic Radiology, University of Iowa Hospitals and Clinics, Iowa City, IA 52242, United StatesAn 83-year old man presented acutely to the emergency department with generalized weakness and subjective fevers. A month earlier he had undergone resection of a large intramuscular sarcoma from his thigh. The cancer staging work-up was still underway and a decision about adjuvant therapy was still pending. Although initial laboratory assessment showed leukocytosis, this normalized soon after admission without the use of antimicrobials. No fevers were documented. During the admission an 18F-FDG PET/CT was performed in continuation of his sarcoma staging workup. This revealed unexpected abnormal radiotracer uptake in the left sternoclavicular joint with fluid collections extending into the sternocleidomastoid muscle and the mediastinum. Imaging findings were consistent with septic arthritis and abscess formation, despite lack of fever or localizing symptoms. Ultrasound-guided aspiration revealed purulent fluid that grew Moraxella nonliquefaciens. Given the unusual presentation, ongoing clinical uncertainty about the true cause of the septic joint, and concern for an occult sarcoma metastasis, surgical debridement and resection of the joint was carried out. Pathology and microbiology evaluation confirmed septic arthritis with osteomyelitis and abscess extension into the mediastinum. No tumor cells were identified. Postoperative course was complicated by hematoma, but otherwise the patient responded well to antimicrobial therapy. Keywords: Moraxella nonliquefaciens, Incidental, Sternoclavicular septic arthritis, F-18 FDG, PET/CThttp://www.sciencedirect.com/science/article/pii/S2214250918300465
collection DOAJ
language English
format Article
sources DOAJ
author Ehab Saad Aldin
Poorani Sekar
Zein Saad Eddin
Jaclyn Keller
Janet Pollard
spellingShingle Ehab Saad Aldin
Poorani Sekar
Zein Saad Eddin
Jaclyn Keller
Janet Pollard
Incidental diagnosis of sternoclavicular septic arthritis with Moraxella nonliquefaciens
IDCases
author_facet Ehab Saad Aldin
Poorani Sekar
Zein Saad Eddin
Jaclyn Keller
Janet Pollard
author_sort Ehab Saad Aldin
title Incidental diagnosis of sternoclavicular septic arthritis with Moraxella nonliquefaciens
title_short Incidental diagnosis of sternoclavicular septic arthritis with Moraxella nonliquefaciens
title_full Incidental diagnosis of sternoclavicular septic arthritis with Moraxella nonliquefaciens
title_fullStr Incidental diagnosis of sternoclavicular septic arthritis with Moraxella nonliquefaciens
title_full_unstemmed Incidental diagnosis of sternoclavicular septic arthritis with Moraxella nonliquefaciens
title_sort incidental diagnosis of sternoclavicular septic arthritis with moraxella nonliquefaciens
publisher Elsevier
series IDCases
issn 2214-2509
publishDate 2018-01-01
description An 83-year old man presented acutely to the emergency department with generalized weakness and subjective fevers. A month earlier he had undergone resection of a large intramuscular sarcoma from his thigh. The cancer staging work-up was still underway and a decision about adjuvant therapy was still pending. Although initial laboratory assessment showed leukocytosis, this normalized soon after admission without the use of antimicrobials. No fevers were documented. During the admission an 18F-FDG PET/CT was performed in continuation of his sarcoma staging workup. This revealed unexpected abnormal radiotracer uptake in the left sternoclavicular joint with fluid collections extending into the sternocleidomastoid muscle and the mediastinum. Imaging findings were consistent with septic arthritis and abscess formation, despite lack of fever or localizing symptoms. Ultrasound-guided aspiration revealed purulent fluid that grew Moraxella nonliquefaciens. Given the unusual presentation, ongoing clinical uncertainty about the true cause of the septic joint, and concern for an occult sarcoma metastasis, surgical debridement and resection of the joint was carried out. Pathology and microbiology evaluation confirmed septic arthritis with osteomyelitis and abscess extension into the mediastinum. No tumor cells were identified. Postoperative course was complicated by hematoma, but otherwise the patient responded well to antimicrobial therapy. Keywords: Moraxella nonliquefaciens, Incidental, Sternoclavicular septic arthritis, F-18 FDG, PET/CT
url http://www.sciencedirect.com/science/article/pii/S2214250918300465
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