The Role of lncRNAs TAPIR-1 and -2 as Diagnostic Markers and Potential Therapeutic Targets in Prostate Cancer

The Role of lncRNAs TAPIR-1 and -2 as Diagnostic Markers and Potential Therapeutic Targets in Prostate Cancer

In search of new biomarkers suitable for the diagnosis and treatment of prostate cancer, genome-wide transcriptome sequencing was carried out with tissue specimens from 40 prostate cancer (PCa) and 8 benign prostate hyperplasia patients. We identified two intergenic long non-coding transcripts, loca...

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Bibliographic Details
Main Authors: Maik Friedrich, Karolin Wiedemann, Kristin Reiche, Sven-Holger Puppel, Gabriele Pfeifer, Ivonne Zipfel, Stefanie Binder, Ulrike Köhl, Gerd A. Müller, Kurt Engeland, Achim Aigner, Susanne Füssel, Michael Fröhner, Claudia Peitzsch, Anna Dubrovska, Michael Rade, Sabina Christ, Stephan Schreiber, Jörg Hackermüller, Jörg Lehmann, Marieta I. Toma, Michael H. Muders, Ulrich Sommer, Gustavo B. Baretton, Manfred Wirth, Friedemann Horn
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Cancers
Subjects:
lncRNA
prostate cancer
diagnostic marker
therapeutic target
p53
cell cycle arrest
Online Access:https://www.mdpi.com/2072-6694/12/5/1122

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