Advances in neurometabolic therapy

Actovegin is a calf blood extract that contains more than 200 biologically active compounds. Experiments have shown that Actovegin reduces the neurotoxic effect of amyloid, neutralizes reactive oxygen species, and normalizes the endothelial function of small vessels. The drug has not been shown to s...

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Bibliographic Details
Main Authors: V. V. Zakharov, N. V. Vakhnina
Format: Article
Language:Russian
Published: IMA-PRESS LLC 2019-11-01
Series:Nevrologiâ, Nejropsihiatriâ, Psihosomatika
Subjects:
Online Access:https://nnp.ima-press.net/nnp/article/view/1187
Description
Summary:Actovegin is a calf blood extract that contains more than 200 biologically active compounds. Experiments have shown that Actovegin reduces the neurotoxic effect of amyloid, neutralizes reactive oxygen species, and normalizes the endothelial function of small vessels. The drug has not been shown to stimulate tumor growth in the neuroblastoma model. Clinical experience with Actovegin suggests that the drug has an undoubted efficacy in treating moderate vascular cognitive impairment and chronic distal symmetric diabetic polyneuropathy and that it is used as additional therapy for primary degenerative and vascular dementia. The clinical efficacy of Actovegin in chronic obliterating diseases of the lowerlimb arteries is being actively studied now.
ISSN:2074-2711
2310-1342