Traditional Chinese Medicine and Gut Microbiome: Their Respective and Concert Effects on Healthcare
Advances in systems biology, particularly based on the omics approaches, have resulted in a paradigm shift in both traditional Chinese medicine (TCM) and the gut microbiome research. In line with this paradigm shift, the importance of TCM and gut microbiome in healthcare, as well as their interplay,...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2020-04-01
|
Series: | Frontiers in Pharmacology |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fphar.2020.00538/full |
id |
doaj-38bd4240c1a74b668b88a22e05b57b2c |
---|---|
record_format |
Article |
spelling |
doaj-38bd4240c1a74b668b88a22e05b57b2c2020-11-25T02:53:59ZengFrontiers Media S.A.Frontiers in Pharmacology1663-98122020-04-011110.3389/fphar.2020.00538535742Traditional Chinese Medicine and Gut Microbiome: Their Respective and Concert Effects on HealthcareRunzhi ZhangXi GaoHong BaiKang NingAdvances in systems biology, particularly based on the omics approaches, have resulted in a paradigm shift in both traditional Chinese medicine (TCM) and the gut microbiome research. In line with this paradigm shift, the importance of TCM and gut microbiome in healthcare, as well as their interplay, has become clearer. Firstly, we briefly summarize the current status of three topics in this review: microbiome, TCM, and relationship of TCM and microbiome. Second, we focused on TCM's therapeutic effects and gut microbiome's mediation roles, including the relationships among diet, gut microbiome, and health care. Third, we have summarized some databases and tools to help understand the impact of TCM and gut microbiome on diagnosis and treatment at the molecular level. Finally, we introduce the effects of gut microbiome on TCM and host health, with two case studies, one on the metabolic effect of gut microbiome on TCM, and another on cancer treatment. In summary, we have reviewed the current status of the two components of healthcare: TCM and gut microbiome, as well as their concert effects. It is quite clear that as the holobiont, the maintenance of the health status of human would depend heavily on TCM, gut microbiome, and their combined effects.https://www.frontiersin.org/article/10.3389/fphar.2020.00538/fulltraditional Chinese medicinegut microbiomehealthcareconcert effectstools and databases |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Runzhi Zhang Xi Gao Hong Bai Kang Ning |
spellingShingle |
Runzhi Zhang Xi Gao Hong Bai Kang Ning Traditional Chinese Medicine and Gut Microbiome: Their Respective and Concert Effects on Healthcare Frontiers in Pharmacology traditional Chinese medicine gut microbiome healthcare concert effects tools and databases |
author_facet |
Runzhi Zhang Xi Gao Hong Bai Kang Ning |
author_sort |
Runzhi Zhang |
title |
Traditional Chinese Medicine and Gut Microbiome: Their Respective and Concert Effects on Healthcare |
title_short |
Traditional Chinese Medicine and Gut Microbiome: Their Respective and Concert Effects on Healthcare |
title_full |
Traditional Chinese Medicine and Gut Microbiome: Their Respective and Concert Effects on Healthcare |
title_fullStr |
Traditional Chinese Medicine and Gut Microbiome: Their Respective and Concert Effects on Healthcare |
title_full_unstemmed |
Traditional Chinese Medicine and Gut Microbiome: Their Respective and Concert Effects on Healthcare |
title_sort |
traditional chinese medicine and gut microbiome: their respective and concert effects on healthcare |
publisher |
Frontiers Media S.A. |
series |
Frontiers in Pharmacology |
issn |
1663-9812 |
publishDate |
2020-04-01 |
description |
Advances in systems biology, particularly based on the omics approaches, have resulted in a paradigm shift in both traditional Chinese medicine (TCM) and the gut microbiome research. In line with this paradigm shift, the importance of TCM and gut microbiome in healthcare, as well as their interplay, has become clearer. Firstly, we briefly summarize the current status of three topics in this review: microbiome, TCM, and relationship of TCM and microbiome. Second, we focused on TCM's therapeutic effects and gut microbiome's mediation roles, including the relationships among diet, gut microbiome, and health care. Third, we have summarized some databases and tools to help understand the impact of TCM and gut microbiome on diagnosis and treatment at the molecular level. Finally, we introduce the effects of gut microbiome on TCM and host health, with two case studies, one on the metabolic effect of gut microbiome on TCM, and another on cancer treatment. In summary, we have reviewed the current status of the two components of healthcare: TCM and gut microbiome, as well as their concert effects. It is quite clear that as the holobiont, the maintenance of the health status of human would depend heavily on TCM, gut microbiome, and their combined effects. |
topic |
traditional Chinese medicine gut microbiome healthcare concert effects tools and databases |
url |
https://www.frontiersin.org/article/10.3389/fphar.2020.00538/full |
work_keys_str_mv |
AT runzhizhang traditionalchinesemedicineandgutmicrobiometheirrespectiveandconcerteffectsonhealthcare AT xigao traditionalchinesemedicineandgutmicrobiometheirrespectiveandconcerteffectsonhealthcare AT hongbai traditionalchinesemedicineandgutmicrobiometheirrespectiveandconcerteffectsonhealthcare AT kangning traditionalchinesemedicineandgutmicrobiometheirrespectiveandconcerteffectsonhealthcare |
_version_ |
1724723276022808576 |