Screening of 22q11.2DS Using Multiplex Ligation-Dependent Probe Amplification as an Alternative Diagnostic Method
Background. The 22q11.2 deletion syndrome (22q11.2DS) is the most common form of deletion disorder in humans. Low copy repeats flanking the 22q11.2 region confers a substrate for nonallelic homologous recombination (NAHR) events leading to rearrangements which have been reported to be associated wit...
Main Authors: | Sathiya Maran, Siti Aisyah Faten, Swee-Hua Erin Lim, Kok-Song Lai, Wan Pauzi Wan Ibrahim, Ravindran Ankathil, Siew Hua Gan, Huay Lin Tan |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2020-01-01
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Series: | BioMed Research International |
Online Access: | http://dx.doi.org/10.1155/2020/6945730 |
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