Clinical observation of hysteroscopic surgery combined with ectopic pregnancy ii decoction and methotrexate in the treatment of cesarean scar pregnancy

Objective: To explore the effectiveness and safety about the treatment of Caesarean Scar Pregnancy combined hysteroscopic surgery with extopic pregnancy Ⅱ decoction and methotrexate(MTX). Methods: A total of 80 cases of CSP patients admitted by our hospital from January 2014 to March 2017 were se...

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Main Authors: Ai-Li Wang, Yan-Xin Chen, Li-Xing Cao
Format: Article
Language:English
Published: Editorial Board of Journal of Hainan Medical University 2018-10-01
Series:Journal of Hainan Medical University
Subjects:
Online Access:http://www.hnykdxxb.com/PDF/201810/09.pdf
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spelling doaj-38fd95fe1b264793bf593e9e05a540422020-11-25T00:46:41ZengEditorial Board of Journal of Hainan Medical UniversityJournal of Hainan Medical University1007-12371007-12372018-10-0124103438Clinical observation of hysteroscopic surgery combined with ectopic pregnancy ii decoction and methotrexate in the treatment of cesarean scar pregnancyAi-Li Wang0Yan-Xin Chen1Li-Xing Cao2Haikou Hospital of Traditional Chinese MedicineHaikou Hospital of Traditional Chinese MedicineHaikou Hospital of Traditional Chinese MedicineObjective: To explore the effectiveness and safety about the treatment of Caesarean Scar Pregnancy combined hysteroscopic surgery with extopic pregnancy Ⅱ decoction and methotrexate(MTX). Methods: A total of 80 cases of CSP patients admitted by our hospital from January 2014 to March 2017 were selected as the subjects. According to the treatment way, the patients were divided into experimental group (n=40) and control group (n=40). The control group was given MTX 50 mg/m2, IM once; and the experimental group was given extopic pregnancy Ⅱ decoction on the basis of the treatment given to the control group; the 8th day hysteroscopic surgery. Routine treatment was given after surgery. Experimental group continued to take extopic pregnancy Ⅱ decoction until monitoring the serum beta-hcg level drops below normal. The general information and curative effect, HCG levels before and after 4, 7 and 11d of treatment; mass diameter before and after 11 d of treatment, menstruation recovery time and the incidence of adverse reactions in 2 groups were observed. Results: After hysteroscopic surgery pretreatment with extopic pregnancy Ⅱ decoction and MTX, HCG levels after 4, 7 and 11d were significantly lower than before, it gradually reduced by time prolonged, and research group was lower than control group, the differences were statistically significant. After treatment with different drugs, the size of pregnancy package in the observation group was significantly smaller than that in the control group. Compared with the control group, the he package block size, beta HCG time and vaginal bleeding time were significantly reduced. Conclusion: It has significant clinical effect of hysteroscopic surgery combined with ectopic pregnancy II and MTX in the treatment of CSP. It has worthy of clinical promotion to control the amount of blood, avoid intrauterine adhesion caused by uterine artery embolization and infection et al and reduce burden of the physical and economic of phttp://www.hnykdxxb.com/PDF/201810/09.pdf Extopic Pregnancy Ⅱ decoctionMethotrexateHysteroscopic SurgeryCaesarean scar pregnancyCesarean scar pregnancyEfficacySafety
collection DOAJ
language English
format Article
sources DOAJ
author Ai-Li Wang
Yan-Xin Chen
Li-Xing Cao
spellingShingle Ai-Li Wang
Yan-Xin Chen
Li-Xing Cao
Clinical observation of hysteroscopic surgery combined with ectopic pregnancy ii decoction and methotrexate in the treatment of cesarean scar pregnancy
Journal of Hainan Medical University
Extopic Pregnancy Ⅱ decoction
Methotrexate
Hysteroscopic Surgery
Caesarean scar pregnancy
Cesarean scar pregnancy
Efficacy
Safety
author_facet Ai-Li Wang
Yan-Xin Chen
Li-Xing Cao
author_sort Ai-Li Wang
title Clinical observation of hysteroscopic surgery combined with ectopic pregnancy ii decoction and methotrexate in the treatment of cesarean scar pregnancy
title_short Clinical observation of hysteroscopic surgery combined with ectopic pregnancy ii decoction and methotrexate in the treatment of cesarean scar pregnancy
title_full Clinical observation of hysteroscopic surgery combined with ectopic pregnancy ii decoction and methotrexate in the treatment of cesarean scar pregnancy
title_fullStr Clinical observation of hysteroscopic surgery combined with ectopic pregnancy ii decoction and methotrexate in the treatment of cesarean scar pregnancy
title_full_unstemmed Clinical observation of hysteroscopic surgery combined with ectopic pregnancy ii decoction and methotrexate in the treatment of cesarean scar pregnancy
title_sort clinical observation of hysteroscopic surgery combined with ectopic pregnancy ii decoction and methotrexate in the treatment of cesarean scar pregnancy
publisher Editorial Board of Journal of Hainan Medical University
series Journal of Hainan Medical University
issn 1007-1237
1007-1237
publishDate 2018-10-01
description Objective: To explore the effectiveness and safety about the treatment of Caesarean Scar Pregnancy combined hysteroscopic surgery with extopic pregnancy Ⅱ decoction and methotrexate(MTX). Methods: A total of 80 cases of CSP patients admitted by our hospital from January 2014 to March 2017 were selected as the subjects. According to the treatment way, the patients were divided into experimental group (n=40) and control group (n=40). The control group was given MTX 50 mg/m2, IM once; and the experimental group was given extopic pregnancy Ⅱ decoction on the basis of the treatment given to the control group; the 8th day hysteroscopic surgery. Routine treatment was given after surgery. Experimental group continued to take extopic pregnancy Ⅱ decoction until monitoring the serum beta-hcg level drops below normal. The general information and curative effect, HCG levels before and after 4, 7 and 11d of treatment; mass diameter before and after 11 d of treatment, menstruation recovery time and the incidence of adverse reactions in 2 groups were observed. Results: After hysteroscopic surgery pretreatment with extopic pregnancy Ⅱ decoction and MTX, HCG levels after 4, 7 and 11d were significantly lower than before, it gradually reduced by time prolonged, and research group was lower than control group, the differences were statistically significant. After treatment with different drugs, the size of pregnancy package in the observation group was significantly smaller than that in the control group. Compared with the control group, the he package block size, beta HCG time and vaginal bleeding time were significantly reduced. Conclusion: It has significant clinical effect of hysteroscopic surgery combined with ectopic pregnancy II and MTX in the treatment of CSP. It has worthy of clinical promotion to control the amount of blood, avoid intrauterine adhesion caused by uterine artery embolization and infection et al and reduce burden of the physical and economic of p
topic Extopic Pregnancy Ⅱ decoction
Methotrexate
Hysteroscopic Surgery
Caesarean scar pregnancy
Cesarean scar pregnancy
Efficacy
Safety
url http://www.hnykdxxb.com/PDF/201810/09.pdf
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