The gut microbiome in atherosclerotic cardiovascular disease

The gut microbiota may play a role in cardiovascular diseases. Here, the authors perform a metagenome-wide association study on stools from individuals with atherosclerotic cardiovascular disease and healthy controls, identifying microbial strains and functions associated with the disease.

Bibliographic Details
Main Authors: Zhuye Jie, Huihua Xia, Shi-Long Zhong, Qiang Feng, Shenghui Li, Suisha Liang, Huanzi Zhong, Zhipeng Liu, Yuan Gao, Hui Zhao, Dongya Zhang, Zheng Su, Zhiwei Fang, Zhou Lan, Junhua Li, Liang Xiao, Jun Li, Ruijun Li, Xiaoping Li, Fei Li, Huahui Ren, Yan Huang, Yangqing Peng, Guanglei Li, Bo Wen, Bo Dong, Ji-Yan Chen, Qing-Shan Geng, Zhi-Wei Zhang, Huanming Yang, Jian Wang, Jun Wang, Xuan Zhang, Lise Madsen, Susanne Brix, Guang Ning, Xun Xu, Xin Liu, Yong Hou, Huijue Jia, Kunlun He, Karsten Kristiansen
Format: Article
Language:English
Published: Nature Publishing Group 2017-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-00900-1
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spelling doaj-3902634aad5d4c37924aa8f6a8a5601b2021-05-11T07:10:06ZengNature Publishing GroupNature Communications2041-17232017-10-018111210.1038/s41467-017-00900-1The gut microbiome in atherosclerotic cardiovascular diseaseZhuye Jie0Huihua Xia1Shi-Long Zhong2Qiang Feng3Shenghui Li4Suisha Liang5Huanzi Zhong6Zhipeng Liu7Yuan Gao8Hui Zhao9Dongya Zhang10Zheng Su11Zhiwei Fang12Zhou Lan13Junhua Li14Liang Xiao15Jun Li16Ruijun Li17Xiaoping Li18Fei Li19Huahui Ren20Yan Huang21Yangqing Peng22Guanglei Li23Bo Wen24Bo Dong25Ji-Yan Chen26Qing-Shan Geng27Zhi-Wei Zhang28Huanming Yang29Jian Wang30Jun Wang31Xuan Zhang32Lise Madsen33Susanne Brix34Guang Ning35Xun Xu36Xin Liu37Yong Hou38Huijue Jia39Kunlun He40Karsten Kristiansen41BGI-ShenzhenBGI-ShenzhenGuangdong Provincial Key Laboratory of Coronary Heart Disease Prevention, Guangdong Cardiovascular InstituteBGI-ShenzhenBGI-ShenzhenBGI-ShenzhenBGI-ShenzhenBGI-ShenzhenBGI-ShenzhenBGI-ShenzhenBGI-ShenzhenBGI-ShenzhenBGI-ShenzhenBGI-ShenzhenBGI-ShenzhenBGI-ShenzhenBGI-ShenzhenBeijing Key Laboratory for Precision Medicine of Chronic Heart Failure, Chinese PLA General HospitalBGI-ShenzhenBGI-ShenzhenBGI-ShenzhenBGI-ShenzhenBGI-ShenzhenBGI-ShenzhenBGI-ShenzhenBGI-ShenzhenGuangdong Provincial Key Laboratory of Coronary Heart Disease Prevention, Guangdong Cardiovascular InstituteGuangdong Provincial Key Laboratory of Coronary Heart Disease Prevention, Guangdong Cardiovascular InstituteGuangdong Provincial Key Laboratory of Coronary Heart Disease Prevention, Guangdong Cardiovascular InstituteBGI-ShenzhenBGI-ShenzhenBGI-ShenzhenDepartment of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical CollegeBGI-ShenzhenDepartment of Biotechnology and Biomedicine, Technical University of Denmark (DTU)Department of Endocrinology and Metabolism, State Key Laboratory of Medical Genomes, National Clinical Research Center for Metabolic Diseases, Shanghai Clinical Center for Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of MedicineBGI-ShenzhenBGI-ShenzhenBGI-ShenzhenBGI-ShenzhenBeijing Key Laboratory for Precision Medicine of Chronic Heart Failure, Chinese PLA General HospitalBGI-ShenzhenThe gut microbiota may play a role in cardiovascular diseases. Here, the authors perform a metagenome-wide association study on stools from individuals with atherosclerotic cardiovascular disease and healthy controls, identifying microbial strains and functions associated with the disease.https://doi.org/10.1038/s41467-017-00900-1
collection DOAJ
language English
format Article
sources DOAJ
author Zhuye Jie
Huihua Xia
Shi-Long Zhong
Qiang Feng
Shenghui Li
Suisha Liang
Huanzi Zhong
Zhipeng Liu
Yuan Gao
Hui Zhao
Dongya Zhang
Zheng Su
Zhiwei Fang
Zhou Lan
Junhua Li
Liang Xiao
Jun Li
Ruijun Li
Xiaoping Li
Fei Li
Huahui Ren
Yan Huang
Yangqing Peng
Guanglei Li
Bo Wen
Bo Dong
Ji-Yan Chen
Qing-Shan Geng
Zhi-Wei Zhang
Huanming Yang
Jian Wang
Jun Wang
Xuan Zhang
Lise Madsen
Susanne Brix
Guang Ning
Xun Xu
Xin Liu
Yong Hou
Huijue Jia
Kunlun He
Karsten Kristiansen
spellingShingle Zhuye Jie
Huihua Xia
Shi-Long Zhong
Qiang Feng
Shenghui Li
Suisha Liang
Huanzi Zhong
Zhipeng Liu
Yuan Gao
Hui Zhao
Dongya Zhang
Zheng Su
Zhiwei Fang
Zhou Lan
Junhua Li
Liang Xiao
Jun Li
Ruijun Li
Xiaoping Li
Fei Li
Huahui Ren
Yan Huang
Yangqing Peng
Guanglei Li
Bo Wen
Bo Dong
Ji-Yan Chen
Qing-Shan Geng
Zhi-Wei Zhang
Huanming Yang
Jian Wang
Jun Wang
Xuan Zhang
Lise Madsen
Susanne Brix
Guang Ning
Xun Xu
Xin Liu
Yong Hou
Huijue Jia
Kunlun He
Karsten Kristiansen
The gut microbiome in atherosclerotic cardiovascular disease
Nature Communications
author_facet Zhuye Jie
Huihua Xia
Shi-Long Zhong
Qiang Feng
Shenghui Li
Suisha Liang
Huanzi Zhong
Zhipeng Liu
Yuan Gao
Hui Zhao
Dongya Zhang
Zheng Su
Zhiwei Fang
Zhou Lan
Junhua Li
Liang Xiao
Jun Li
Ruijun Li
Xiaoping Li
Fei Li
Huahui Ren
Yan Huang
Yangqing Peng
Guanglei Li
Bo Wen
Bo Dong
Ji-Yan Chen
Qing-Shan Geng
Zhi-Wei Zhang
Huanming Yang
Jian Wang
Jun Wang
Xuan Zhang
Lise Madsen
Susanne Brix
Guang Ning
Xun Xu
Xin Liu
Yong Hou
Huijue Jia
Kunlun He
Karsten Kristiansen
author_sort Zhuye Jie
title The gut microbiome in atherosclerotic cardiovascular disease
title_short The gut microbiome in atherosclerotic cardiovascular disease
title_full The gut microbiome in atherosclerotic cardiovascular disease
title_fullStr The gut microbiome in atherosclerotic cardiovascular disease
title_full_unstemmed The gut microbiome in atherosclerotic cardiovascular disease
title_sort gut microbiome in atherosclerotic cardiovascular disease
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2017-10-01
description The gut microbiota may play a role in cardiovascular diseases. Here, the authors perform a metagenome-wide association study on stools from individuals with atherosclerotic cardiovascular disease and healthy controls, identifying microbial strains and functions associated with the disease.
url https://doi.org/10.1038/s41467-017-00900-1
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